Guo Liang, Xu Lei, Liu Liying
Key Laboratory for Micro and Nanophotonic Structures (Ministry of Education, China), Department of Optical Science and Engineering, School of Information Science and Engineering, Fudan University, Shanghai 200433, China.
Department of Physics, Fudan University, Shanghai 200433, China.
Sensors (Basel). 2025 Jul 14;25(14):4386. doi: 10.3390/s25144386.
This paper reports on the high performance of a thick-waveguide guided mode resonance (GMR) sensor. Theoretical calculations revealed that when light incidents on the grating and excites the negative first-order diffraction order, by increasing the waveguide thickness, both a high sensitivity and high figure of merit (FOM) can be obtained. Experimentally, we achieved a sensitivity of 1255.78 nm/RIU, a resonance linewidth of 0.59 nm at the resonance wavelength of 535 nm, an FOM as high as 2128 RIU, and a detection limit as low as 1.74 × 10 RIU. To our knowledge, this performance represents the highest comprehensive level for current GMR sensors. Additionally, the use of a microfluidic hemisphere and polymer materials effectively reduces the liquid consumption under oblique incidence and the fabrication cost in practical application. Overall, the proposed GMR sensor exhibits great potential in label-free biosensing.
本文报道了一种厚波导导模共振(GMR)传感器的高性能。理论计算表明,当光入射到光栅上并激发负一阶衍射级时,通过增加波导厚度,可以获得高灵敏度和高品质因数(FOM)。实验上,我们实现了1255.78 nm/RIU的灵敏度、在535 nm共振波长处0.59 nm的共振线宽、高达2128 RIU的品质因数以及低至1.74×10 RIU的检测限。据我们所知,这种性能代表了当前GMR传感器的最高综合水平。此外,微流体半球和聚合物材料的使用有效地减少了斜入射下的液体消耗以及实际应用中的制造成本。总体而言,所提出的GMR传感器在无标记生物传感方面具有巨大潜力。