Gou Ruoyu, Luo Changjun, Liang Xudong, Qin Shuitao, Wu Hao, Li Bing, Pan Fengqi, Li Jinwei, Chen Jun-An
School of Public Health, Ningxia Medical University, Yinchuan, Ningxia, China.
Department of Cardiology, Affiliated Liutie Central Hospital of Guangxi Medical University, Liuzhou, China.
Front Aging. 2025 Jul 15;6:1489914. doi: 10.3389/fragi.2025.1489914. eCollection 2025.
Stroke is a serious disease that negatively affects the quality of life of patients and has become a global public health problem. This study used data from the 2021 Global Burden of Disease (GBD) study to assess the burden of stroke in the elderly population between 1990 and 2021.
This cross-sectional study utilised data from the Global Burden of Disease (GBD) 2021, encompassing 204 countries and territories. The analysis included data from older patients who had experienced a stroke. The analysis includes morbidity, all-cause and cause-specific mortality, disability-adjusted life years, and corresponding estimated annual percentage changes (APCs).
From 1990 to 2021, the total number of stroke cases among the global elderly population rose from approximately 4.39 million to 8.19 million, with the age-standardized incidence (ASIR) decreasing from 996.06 cases per 100,000 people to 775.68 cases per 100,000 people (EAPC-0.784). The number of deaths increased from 4.08 million to 6.19 million, and the age-standardized mortality rate (ASMR) decreased from 981.87 to 600.08 deaths per 100,000 people (EAPC-1.446). The number of disability-adjusted life years (DALYs) increased from 75.96 million to approximately 111.14 million, with the age-standardized DALYs rate (ASDR) declining (EAPC-1.596). In five Socio-Demographic Index (SDI) regions, the disease burden was higher in men than in women.
The number of stroke cases, deaths and DALYs increased in the elderly, while the global incidence, mortality and mortality rates of stroke decreased, with a higher burden on older men than women.
中风是一种严重疾病，会对患者生活质量产生负面影响，已成为全球公共卫生问题。本研究使用2021年全球疾病负担（GBD）研究的数据，评估1990年至2021年老年人群的中风负担。
这项横断面研究利用了来自204个国家和地区的2021年全球疾病负担（GBD）数据。分析纳入了经历过中风的老年患者的数据。分析内容包括发病率、全因死亡率和特定病因死亡率、伤残调整生命年以及相应的年度估计百分比变化（APC）。
1990年至2021年，全球老年人群中风病例总数从约439万增至819万，年龄标准化发病率（ASIR）从每10万人996.06例降至每10万人775.68例（EAPC为 -0.784）。死亡人数从408万增至619万，年龄标准化死亡率（ASMR）从每10万人981.87例降至每10万人600.08例（EAPC为 -1.446）。伤残调整生命年（DALYs）从7596万增至约1.1114亿，年龄标准化DALYs率（ASDR）下降（EAPC为 -1.596）。在五个社会人口指数（SDI）区域，男性疾病负担高于女性。
老年人群中中风病例数、死亡数和伤残调整生命年增加，而全球中风发病率、死亡率和死亡率下降，老年男性负担高于女性。
