Okunade Kehinde Sharafadeen, Sunmonu Halimah O, Ajileye Oluwaseun, Fayinto Ayomide, Adetula Oluwatosin, Adegbola Omololu
Department of Obstetrics and Gynaecology, College of Medicine, University of Lagos, Lagos, Nigeria.
Department of Obstetrics and Gynaecology, Lagos University Teaching Hospital, Lagos, Nigeria.
J Clin Sci. 2024 Oct-Dec;21(4):180-184. doi: 10.4103/jcls.jcls_46_24. Epub 2024 Oct 24.
The significant burden and adverse outcomes of infection during pregnancy highlight the urgent need to understand the factors contributing to its widespread occurrence. Our study determined the prevalence of infection among parturients using the novel rapid test, and then assessed associated factors among parturients in Lagos, Nigeria.
This multicenter descriptive cross-sectional study enrolled = 188 parturients in the labor ward of three hospitals in Lagos, Southwest Nigeria, from April 2021 to December 2021. We identified factors significantly associated with infection using the multivariable binary logistic regression model with a backward stepwise selection approach.
The study revealed a 7.4% (95% confidence interval: 4.1-12.2) prevalence of infection. The only factor independently associated with infection was a history of term or preterm prelabor rupture of membranes (PROM) in the index pregnancy (adjusted odds ratio = 11.38, 95% confidence interval: 2.15-60.17).
One in 13 parturient women in our study had infection, with a notable association with preterm or term PROM. Our findings, however, underscore the need for further research with a larger sample size to understand the causal pathways and broader risk factors associated with infection, informing more effective public health strategies.
孕期感染带来的重大负担和不良后果凸显了迫切需要了解导致其广泛发生的因素。我们的研究使用新型快速检测方法确定了产妇中感染的患病率,然后评估了尼日利亚拉各斯产妇中的相关因素。
这项多中心描述性横断面研究于2021年4月至2021年12月在尼日利亚西南部拉各斯的三家医院的产房招募了188名产妇。我们使用多变量二元逻辑回归模型和向后逐步选择方法确定了与感染显著相关的因素。
研究显示感染患病率为7.4%(95%置信区间:4.1 - 12.2)。与感染独立相关的唯一因素是本次妊娠足月或早产胎膜早破(PROM)史(调整比值比 = 11.38,95%置信区间:2.15 - 60.17)。
在我们的研究中,每13名产妇中有1人感染,与早产或足月PROM有显著关联。然而,我们的研究结果强调需要进行更大样本量的进一步研究,以了解与感染相关的因果途径和更广泛的风险因素,并为更有效的公共卫生策略提供依据。