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一项关于前交叉韧带重建中一种新型髌下脂肪垫保留技术可减轻术后疼痛并减少软骨损伤的回顾性研究。

A novel infrapatellar fat pad preservation technique in anterior cruciate ligament reconstruction reduces postoperative pain and cartilage damage: a retrospective study.

作者信息

Li Shilin, Lu Mingfeng, Zhao Lilian, He Lilei, Fan Weifeng, Zhou Jie, Yan Sumin

机构信息

The Eighth Clinical Medical College of Guangzhou University of Chinese Medicine, 6 QinRen Road, ZuMiao Street, Foshan, Guangdong, 528000, China.

Foshan Hospital of Traditional Chinese Medicine, 6 QinRen Road, ZuMiao Street, Foshan, Guangdong, 528000, China.

出版信息

J Orthop Surg Res. 2025 Aug 5;20(1):728. doi: 10.1186/s13018-025-06162-8.

Abstract

OBJECTIVE

To introduce a novel infrapatellar fat pad (IPFP) preservation technique for anterior cruciate ligament reconstruction (ACLR) and evaluate its efficacy in reducing postoperative pain and enhancing functional recovery of the knee, assessing its impact on postoperative IPFP fibrosis, intra-articular inflammation, and cartilage degeneration progression.

METHODS

This study included 86 anterior cruciate ligament (ACL) tear patients treated at Foshan Hospital of Traditional Chinese Medicine between May 2019 and June 2022. Patients were divided into two groups, the IPFP preservation group (n = 42) and the non-preservation group (n = 44), on the basis of how the IPFP was managed during surgery. The duration of the operations was recorded for both groups. Comparative assessments included the Kujala score, International Knee Documentation Committee (IKDC) score, KT-1000 arthrometer measurements, visual analogue scale (VAS) score, and range of motion (ROM). Additionally, at the 12-month follow-up, synovial fluid IL-6 levels and IPFP fibrosis grading were compared. Cartilage health was evaluated by the ICRS, and the proportion of patients showing cartilage deterioration was compared.

RESULTS

There were no significant differences between the two groups in terms of baseline characteristics, surgical duration (P = 0.12), IKDC score (P = 0.80), KT-1000 laxity (P = 0.09). No statistically significant differences in ROM were observed between the two groups at both the 12-month (P = 0.10) and final follow-up (P = 0.19). However, the preservation group had higher Kujala scores (P = 0.01), lower VAS scores (P = 0.00) and significantly improved ROM at 3 and 6 months (P = 0.04, P = 0.00) postoperatively. At the 1-year assessment, the preservation group had notably lower levels of synovial IL-6 (P = 0.00), reduced progression of IPFP fibrosis (P = 0.00), decreased severity of chondral lesions (P = 0.00) and a lower proportion of patients with progressive cartilage deterioration (P = 0.00) than did the non-preservation group.

CONCLUSION

This technique represents an effective novel approach for preserving the IPFP. It can significantly reduce IPFP fibrosis, enhance postoperative functional recovery following ACLR, and alleviate knee pain along with cartilage damage.

摘要

目的

介绍一种用于前交叉韧带重建(ACLR)的新型髌下脂肪垫(IPFP)保留技术,并评估其在减轻术后疼痛和促进膝关节功能恢复方面的疗效,同时评估其对术后IPFP纤维化、关节内炎症和软骨退变进展的影响。

方法

本研究纳入了2019年5月至2022年6月在佛山市中医院接受治疗的86例前交叉韧带(ACL)撕裂患者。根据手术中IPFP的处理方式,将患者分为两组,即IPFP保留组(n = 42)和非保留组(n = 44)。记录两组的手术时长。比较评估指标包括库贾拉评分、国际膝关节文献委员会(IKDC)评分、KT-1000关节测径仪测量结果、视觉模拟量表(VAS)评分和活动范围(ROM)。此外,在12个月随访时,比较两组的滑液白细胞介素-6水平和IPFP纤维化分级。通过国际软骨修复协会(ICRS)评估软骨健康状况,并比较出现软骨退变的患者比例。

结果

两组在基线特征、手术时长(P = 0.12)、IKDC评分(P = 0.80)、KT-1000松弛度(P = 0.09)方面无显著差异。在12个月(P = 0.10)和最终随访时(P = 0.19),两组在ROM方面均未观察到统计学显著差异。然而,保留组的库贾拉评分更高(P = 0.01),VAS评分更低(P = 0.00),且术后3个月和6个月时ROM显著改善(P = 0.04,P = 0.00)。在1年评估时,保留组的滑液白细胞介素-6水平显著更低(P = 0.00),IPFP纤维化进展减轻(P = 0.00),软骨损伤严重程度降低(P = 0.00),且出现软骨进行性退变的患者比例更低(P = 0.00)。

结论

该技术是一种有效的保留IPFP的新方法。它可显著减少IPFP纤维化,增强ACLR术后的功能恢复,并减轻膝关节疼痛和软骨损伤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7e3/12326706/c726e2d1b818/13018_2025_6162_Fig1_HTML.jpg

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