用于放射学研究的兔脑肿瘤模型的建立。
Development of rabbit brain tumor model for radiologic research.
作者信息
Cochran S T, Higashida R T, Holburt E, Winter J, Iwamoto K, Norman A
出版信息
Invest Radiol. 1985 Dec;20(9):928-32. doi: 10.1097/00004424-198512000-00007.
Abstract
A rabbit brain tumor model using transplanted VX-2 carcinoma had an 85% rate of successful implantation. Rabbits lived 8.5 +/- 1.3 days. The tumor doubling time was 0.5 to 2.6 days. Some tumors were shown as early as four days after implantation and all tumors were seen by ten days after implantation. Two of three rabbits receiving radiation therapy to the tumor had significant extension of life. This model is a useful radiologic research tool.
摘要
使用移植VX-2癌构建的兔脑肿瘤模型，植入成功率为85%。兔子存活8.5±1.3天。肿瘤倍增时间为0.5至2.6天。有些肿瘤在植入后四天即可显示，所有肿瘤在植入后十天均可看到。接受肿瘤放射治疗的三只兔子中有两只寿命显著延长。该模型是一种有用的放射学研究工具。
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