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兽医学中纳米凝胶的最新进展。

Recent advances in nanogels in veterinary medicine.

作者信息

Soriano Pérez Maria Laura, Flores Bracamonte Maria Carolina, Bellingeri Romina, Alustiza Fabrisio, Molina Maria

机构信息

Grupo Sanidad Animal, INTA Marcos Juárez, Córdoba, Argentina.

Instituto de Investigaciones en Tecnologías Energéticas y Materiales Avanzados (IITEMA), Universidad Nacional de Río Cuarto (UNRC) - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Río Cuarto, Córdoba, Argentina.

出版信息

Vet Res. 2025 Aug 7;56(1):164. doi: 10.1186/s13567-025-01576-y.

Abstract

Nanogels, a promising class of nanomaterials, have emerged as versatile platforms in veterinary medicine and have shown substantial progress in recent years. This review outlines the key developments and potential applications of nanogels in veterinary therapeutics. It provides an in-depth discussion of critical factors influencing nanogel implementation, including synthesis, biocompatibility, biodegradability, clinical translation, and technological considerations. Approaches to nanogel-based vaccines and drug-delivery systems are examined, with particular emphasis on the mucosal route of administration, given its relevance in livestock. Finally, the integration of nanogels into the One Health framework is considered.

摘要

纳米凝胶作为一类很有前景的纳米材料,已成为兽医学中的通用平台,并且近年来已取得了重大进展。本综述概述了纳米凝胶在兽医治疗中的关键进展和潜在应用。它深入讨论了影响纳米凝胶应用的关键因素,包括合成、生物相容性、生物降解性、临床转化和技术考量。研究了基于纳米凝胶的疫苗和药物递送系统的方法,鉴于其在牲畜中的相关性,特别强调了粘膜给药途径。最后,考虑了将纳米凝胶整合到“同一个健康”框架中。

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