Al-Ajmi Fatema, Al Moqbali Abdulmalik, Al Abri Mohammed, Al Waili Khalid, Al Rasadi Khalid, Al Hashmi Khamis
College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman.
Department of Physiology, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman.
Oman Med J. 2025 Mar 31;40(2):e734. doi: 10.5001/omj.2025.63. eCollection 2025 Mar.
This study aimed to evaluate the screening rate and the prevalence of obstructive sleep apnea syndrome (OSAS) in patients with apparent resistant hypertension (ARH) attending Sultan Qaboos University Hospital, and to assess sex differences.
A cross-sectional retrospective study was conducted using the data from 500 patients with ARH between January 2018 and January 2023. The cohort included 270 women and 230 men. Data extracted from hospital records included demographic and clinical characteristics, antihypertensive medications, results of OSA screening tools (e.g., Epworth Sleepiness Scale and STOP-Bang questionnaire), and polysomnography outcomes.
Of the 500 patients with ARH, 54 (10.8%) were diagnosed with OSAS. Only 6.6% (n = 33) were screened for OSA using the Epworth Sleepiness Scale or STOP-Bang questionnaire, while the majority (93.4%, n = 467) were not screened. Women constituted 54.0% of the cohort and had a higher mean body mass index than men (32.7 kg/m vs. 30.2 kg/m, < 0.001). OSAS prevalence was significantly higher in women than men (14.1% vs. 7.0%, 0.013).
There was a low rate of screening for OSAS among patients with ARH at Sultan Qaboos University Hospital, which may explain the lower-than-expected prevalence observed. Contrary to published literature, OSAS was more frequently diagnosed in women, who were screened more often, suggesting that OSA may be underdiagnosed in men.
本研究旨在评估就诊于苏丹卡布斯大学医院的明显难治性高血压(ARH)患者的阻塞性睡眠呼吸暂停综合征(OSAS)筛查率及患病率,并评估性别差异。
采用回顾性横断面研究,收集2018年1月至2023年1月期间500例ARH患者的数据。该队列包括270名女性和230名男性。从医院记录中提取的数据包括人口统计学和临床特征、抗高血压药物、OSA筛查工具(如爱泼华嗜睡量表和STOP-Bang问卷)的结果以及多导睡眠图结果。
在500例ARH患者中,54例(10.8%)被诊断为OSAS。仅6.6%(n = 33)使用爱泼华嗜睡量表或STOP-Bang问卷进行了OSA筛查,而大多数(93.4%,n = 467)未进行筛查。女性占队列的54.0%,平均体重指数高于男性(32.7kg/m²对30.2kg/m²,P < 0.001)。女性的OSAS患病率显著高于男性(14.1%对7.0%,P = 0.013)。
苏丹卡布斯大学医院ARH患者的OSAS筛查率较低,这可能解释了观察到的患病率低于预期的原因。与已发表的文献相反,OSAS在女性中诊断更为频繁,且女性接受筛查的频率更高,这表明男性的OSA可能未得到充分诊断。