Mo Cheng, Liu Guangyu, Huang He
Anesthesiology, Guangxi Zhuang Autonomous Region People's Hospital, Nanning, Guangxi, China.
Anesthesiology, Chinese Academy of Medical Sciences & Peking Union Medical College Fuwai Hospital, Xicheng, Beijing, China
BMJ Open. 2025 Aug 24;15(8):e087603. doi: 10.1136/bmjopen-2024-087603.
Breech presentation, occurring in approximately 3-5% of term pregnancies, is associated with increased risks of complications during vaginal delivery, including challenges in delivering the aftercoming head, umbilical cord prolapse, birth trauma and neonatal asphyxia. External cephalic version (ECV) is a recommended procedure to reposition the fetus from a non-cephalic to a cephalic presentation, aiming to reduce the risks associated with breech presentation and increase the likelihood of a vaginal delivery. We aimed to determine the impact of neuraxial analgesia on the success rate and safety of ECV by conducting a systematic review and network meta-analysis.
A comprehensive search will be conducted in electronic databases such as Cochrane Central Register of Controlled Trials (The Cochrane Library), PubMed, Web of Science and Embase. Studies investigating the effects of neuraxial analgesia, including spinal and epidural analgesia, on ECV success rates and patient safety will be included. The primary outcome is the success rate of ECV, while secondary outcomes include adverse events, complications and maternal and fetal well-being.
Ethical approval is not required as this review will analyse existing literature without patient involvement. The findings, which aim to assess the effects of neuraxial analgesia in ECV procedures, are expected to inform clinical practice and improve patient care. The results will be disseminated through publication in a peer-reviewed journal and presentation at relevant conferences.
CRD42023047525.
臀位分娩约占足月妊娠的3%-5%,与阴道分娩期间并发症风险增加相关,包括娩出后出头困难、脐带脱垂、产伤和新生儿窒息。外倒转术(ECV)是一种推荐的将胎儿从非头位转为头位的操作,旨在降低与臀位分娩相关的风险并增加阴道分娩的可能性。我们旨在通过进行系统评价和网状荟萃分析来确定神经轴阻滞对ECV成功率和安全性的影响。
将在电子数据库中进行全面检索,如Cochrane对照试验中心注册库(Cochrane图书馆)、PubMed、科学引文索引和Embase。纳入研究神经轴阻滞(包括脊髓和硬膜外阻滞)对ECV成功率和患者安全性影响的研究。主要结局是ECV的成功率,次要结局包括不良事件、并发症以及母婴健康状况。
由于本评价将分析现有文献且不涉及患者,因此无需伦理批准。旨在评估神经轴阻滞在ECV操作中的作用的研究结果有望为临床实践提供参考并改善患者护理。研究结果将通过在同行评审期刊上发表以及在相关会议上报告进行传播。
PROSPERO注册号:CRD42023047525。