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一名患有多发性动脉瘤患者的胃网膜动脉急性炎性假性动脉瘤:一个突出全身血管重塑的病例

Acute Inflammatory Pseudoaneurysm of the Gastroepiploic Artery in a Patient with Multiple Aneurysms: A Case Highlighting Systemic Vascular Remodeling.

作者信息

Yoshida Yuri, Kikuchi Shinsuke, Uchida Daiki, Kuriyama Naoya, Tada Yuki, Koya Atsuhiro, Yuzawa Sayaka, Uchida Hisashi, Tanino Mishie, Azuma Nobuyoshi

机构信息

Department of Vascular Surgery, Asahikawa Medical University, Asahikawa, Hokkaido, Japan.

Department of Cardiovascular Surgery, Sapporo Kosei General Hospital, Sapporo, Hokkaido, Japan.

出版信息

Ann Vasc Dis. 2025;18(1). doi: 10.3400/avd.cr.25-00072. Epub 2025 Aug 20.

Abstract

A 52-year-old man with scoliosis and psoriasis vulgaris, treated with infliximab, presented with a large right gastroepiploic artery aneurysm (GEAA). Following surgical resection, additional aneurysms of the anterior communicating artery and abdominal aorta were identified. Histopathological examination revealed a pseudoaneurysm with organizing thrombus and marked acute inflammation, including neutrophilic infiltration of the medial wall. Despite negative cultures, an infection-related vascular insult could not be excluded. This case highlights a rare immune-mediated vascular pathology in the context of chronic inflammatory disease, emphasizing the potential role of acute inflammation and psoriasis-associated immune dysregulation in visceral artery aneurysm formation.

摘要

一名52岁患有脊柱侧弯和寻常型银屑病的男性,接受英夫利昔单抗治疗,出现了一个巨大的右胃网膜动脉瘤(GEAA)。手术切除后,发现前交通动脉和腹主动脉还有其他动脉瘤。组织病理学检查显示为一个伴有机化血栓和明显急性炎症的假性动脉瘤,包括中膜壁的中性粒细胞浸润。尽管培养结果为阴性,但不能排除感染相关的血管损伤。该病例突出了慢性炎症性疾病背景下一种罕见的免疫介导的血管病变,强调了急性炎症和银屑病相关免疫失调在内脏动脉瘤形成中的潜在作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bcc/12375504/646bf8350f1a/avd-18-1-25-00072-figure01.jpg

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