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外语综合征:神经学与精神病学方面

Foreign Language Syndrome: Neurological and Psychiatric Aspects.

作者信息

Eghzawi Ansam, Madha Ali, Aburashed Rany

机构信息

Neurogen Biomarking LLC, Dover, DE 19901, USA.

Insight Hospital and Medical Center, Chicago, IL 60616, USA.

出版信息

Neurol Int. 2025 Aug 6;17(8):122. doi: 10.3390/neurolint17080122.

Abstract

Foreign Language Syndrome (FLS) is a rare neuropsychiatric condition characterized by the sudden, involuntary use of a non-native language, with concurrent loss or suppression of the native language. Distinct from Foreign Accent Syndrome (FAS), FLS often arises acutely following anesthesia, brain injury, or psychological stress. Although neuroimaging typically reveals no structural pathology, functional disconnection within bilingual language control systems has been hypothesized. Case reports suggest contributions from both neurological disruptions-such as transient cortical dysfunction-and psychiatric mechanisms, including dissociation and conversion phenomena. This review synthesizes the clinical features, diagnostic strategies, neurocognitive models, and psychiatric interpretations of FLS. It emphasizes the importance of multidisciplinary evaluation and treatment and outlines prognosis patterns. The need for longitudinal follow-up, functional imaging studies, and centralized case databases is highlighted to better understand the pathophysiology and clinical management of this enigmatic syndrome.

摘要

外语综合征(FLS)是一种罕见的神经精神疾病,其特征是突然、非自主地使用非母语,同时母语出现丧失或受到抑制。与外国口音综合征(FAS)不同,FLS通常在麻醉、脑损伤或心理压力后急性发作。尽管神经影像学检查通常未发现结构病变,但已有假说认为双语语言控制系统内存在功能脱节。病例报告表明,神经功能紊乱(如短暂性皮质功能障碍)和精神机制(包括分离和转换现象)都有影响。本综述综合了FLS的临床特征、诊断策略、神经认知模型和精神学解释。强调了多学科评估和治疗的重要性,并概述了预后模式。强调需要进行纵向随访、功能成像研究以及建立集中的病例数据库,以更好地了解这种神秘综合征的病理生理学和临床管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5647/12388630/a1052607eb3d/neurolint-17-00122-g001.jpg

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