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整块切除骨巨细胞瘤后采用非血管化腓骨近端自体骨移植重建桡骨远端:一项回顾性研究

Distal Radius Reconstruction With Non-vascularized Proximal Fibular Autograft After en-Bloc Resection of Giant Cell Tumors: A Retrospective Study.

作者信息

Shahid Ul Islam Mir, Sidhu Vishal, Akbar Naim, Hussain Altaf, Huda Najamul, Choudary Goduguluri Naveen Kumar, Faizullah Mohd, Ul Huda Mohd Ashar

机构信息

Orthopaedics, Venkateshwara Institute of Medical Sciences, Gajraula, IND.

Medicine and Surgery, Jawaharlal Nehru Medical College, Aligarh, IND.

出版信息

Cureus. 2025 Jul 27;17(7):e88840. doi: 10.7759/cureus.88840. eCollection 2025 Jul.

Abstract

Background Giant cell tumors (GCTs) of the distal radius present significant reconstructive challenges following wide resection. Proximal fibular autograft reconstruction has been a biologically compatible solution, particularly valuable in resource-limited settings. This study evaluates clinical and functional outcomes of this technique. Materials and methods We retrospectively analyzed 14 patients (10 females, four males; mean age 30.9±5.4 years) with eight Campanacci grade II (57.1%) and six patients of grade III (42.9%) distal radius GCTs treated with en-bloc resection and proximal fibular autograft reconstruction. Outcomes were assessed using Musculoskeletal Tumor Society (MSTS) scores, range of motion (ROM) measurements, grip strength, and complication rates. Results Mean MSTS score was 20.6±2.9 (range 15-24). Mean wrist ROM included flexion 28.2°±7.0°, extension 20.7°±6.1°, radial deviation 10.1°±3.3°, and ulnar deviation 10.0°±4.4°. Forearm rotation was well preserved (supination 45.4°±14.7°, pronation 49.6°±10.5°). Grip strength averaged 60.9%±7.4% of the contralateral side. Complications included seven fibula-carpal subluxations (50%), four fibula-ulnar diastases (28.6%), one non-union (7.1%), and one transient foot drop (7.1%). The majority of our patients (n=11, 78.5%) were either pain-free or had mild pain, while only three patients (21.5%) had moderate pain, with none having intolerable pain. All patients achieved independence in activities of daily living. Among seven manual laborers, four returned to their original work while three required modifications; all non-manual workers resumed pre-operative activities. Conclusion En-bloc resection and proximal fibular autograft reconstruction for distal radius GCTs provide satisfactory functional outcomes with acceptable complication rates. While wrist mobility shows some limitation compared to normal values, most patients achieve good functional recovery and return to daily activities.

摘要

背景 桡骨远端骨巨细胞瘤(GCTs)在广泛切除后带来了重大的重建挑战。腓骨近端自体骨移植重建是一种生物相容性良好的解决方案,在资源有限的环境中尤其有价值。本研究评估了该技术的临床和功能结果。

材料与方法 我们回顾性分析了14例患者(10例女性,4例男性;平均年龄30.9±5.4岁),他们患有8例Campanacci II级(57.1%)和6例III级(42.9%)的桡骨远端GCTs,接受了整块切除和腓骨近端自体骨移植重建。使用肌肉骨骼肿瘤学会(MSTS)评分、活动范围(ROM)测量、握力和并发症发生率来评估结果。

结果 平均MSTS评分为20.6±2.9(范围15 - 24)。平均腕关节ROM包括屈曲28.2°±7.0°、伸展20.7°±6.1°、桡偏10.1°±3.3°和尺偏10.0°±4.4°。前臂旋转保留良好(旋后45.4°±14.7°,旋前49.6°±10.5°)。握力平均为对侧的60.9%±7.4%。并发症包括7例腓骨 - 腕关节半脱位(50%)、4例腓骨 - 尺骨分离(28.6%)、1例骨不连(7.1%)和1例短暂性足下垂(7.1%)。我们的大多数患者(n = 11,78.5%)无痛或仅有轻度疼痛,而只有3例患者(21.5%)有中度疼痛,无患者有难以忍受的疼痛。所有患者在日常生活活动中均实现了自理。在7名体力劳动者中,4人恢复了原工作,3人需要调整工作;所有非体力劳动者都恢复了术前活动。

结论 对于桡骨远端GCTs,整块切除和腓骨近端自体骨移植重建提供了令人满意的功能结果,并发症发生率可接受。虽然与正常值相比腕关节活动度有一定限制,但大多数患者实现了良好的功能恢复并恢复了日常活动。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/573f/12378932/f4d62553fe0b/cureus-0017-00000088840-i01.jpg

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