五年后：长期新冠没有简单答案。 - Suppr

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Five years later: no short answers for Long COVID.

作者信息

Sala Marc A, Koralnik Igor J

机构信息

Division of Pulmonary and Critical Care, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Comprehensive COVID Center, Northwestern Medicine, Chicago, IL, USA.

出版信息

Geroscience. 2025 Aug 28. doi: 10.1007/s11357-025-01870-9.

DOI:10.1007/s11357-025-01870-9

PMID:40875136

Abstract

摘要

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本文引用的文献

Non-Hospitalized Long COVID Patients Exhibit Reduced Retinal Capillary Perfusion: A Prospective Cohort Study.

J Imaging. 2025 Feb 17;11(2):62. doi: 10.3390/jimaging11020062.

Author Correction: Profibrotic monocyte-derived alveolar macrophages are expanded in patients with persistent respiratory symptoms and radiographic abnormalities after COVID-19.

Nat Immunol. 2025 Feb;26(2):323. doi: 10.1038/s41590-025-02076-z.

Neurologic Manifestations of Long COVID Disproportionately Affect Young and Middle-Age Adults.

Ann Neurol. 2025 Feb;97(2):369-383. doi: 10.1002/ana.27128. Epub 2024 Nov 22.

Active Surveillance or Watchful Waiting for Intermediate-Risk Prostate Cancer, 2010-2020.

JAMA. 2024 Dec 17;332(23):2033-2036. doi: 10.1001/jama.2024.20580.

Mechanisms of long COVID and the path toward therapeutics.

Cell. 2024 Oct 3;187(20):5500-5529. doi: 10.1016/j.cell.2024.07.054. Epub 2024 Sep 25.

Long COVID science, research and policy.

Nat Med. 2024 Aug;30(8):2148-2164. doi: 10.1038/s41591-024-03173-6. Epub 2024 Aug 9.

Long COVID as a disease of accelerated biological aging: An opportunity to translate geroscience interventions.

Ageing Res Rev. 2024 Aug;99:102400. doi: 10.1016/j.arr.2024.102400. Epub 2024 Jun 28.

Long COVID and its association with neurodegenerative diseases: pathogenesis, neuroimaging, and treatment.

Front Neurol. 2024 Apr 4;15:1367974. doi: 10.3389/fneur.2024.1367974. eCollection 2024.

Plasma proteomics show altered inflammatory and mitochondrial proteins in patients with neurologic symptoms of post-acute sequelae of SARS-CoV-2 infection.

Brain Behav Immun. 2023 Nov;114:462-474. doi: 10.1016/j.bbi.2023.08.022. Epub 2023 Sep 11.

Long COVID and older people.

Lancet Healthy Longev. 2022 Dec;3(12):e849-e854. doi: 10.1016/S2666-7568(22)00245-8.

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相似文献

Five years later: no short answers for Long COVID.

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Cochrane Database Syst Rev. 2023 Aug 16;8(8):CD015102. doi: 10.1002/14651858.CD015102.pub2.

Vaccines for preventing infections in adults with haematological malignancies.

Cochrane Database Syst Rev. 2025 May 21;5(5):CD015530. doi: 10.1002/14651858.CD015530.pub2.

Early versus late tracheostomy in critically ill COVID-19 patients.

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Interventions to prevent obesity in children aged 5 to 11 years old.

Cochrane Database Syst Rev. 2024 May 20;5(5):CD015328. doi: 10.1002/14651858.CD015328.pub2.

Nirmatrelvir combined with ritonavir for preventing and treating COVID-19.

Cochrane Database Syst Rev. 2022 Sep 20;9(9):CD015395. doi: 10.1002/14651858.CD015395.pub2.

Nirmatrelvir combined with ritonavir for preventing and treating COVID-19.

Cochrane Database Syst Rev. 2023 Nov 30;11(11):CD015395. doi: 10.1002/14651858.CD015395.pub3.

Outcomes of specialist physiotherapy for functional motor disorder: the Physio4FMD RCT.

Health Technol Assess. 2025 Jul;29(34):1-28. doi: 10.3310/MKAC9495.

Vaccines for preventing infections in adults with solid tumours.

Cochrane Database Syst Rev. 2025 Apr 16;4(4):CD015551. doi: 10.1002/14651858.CD015551.pub2.

Cardiovascular training for fatigue in people with cancer.

Cochrane Database Syst Rev. 2025 Feb 20;2(2):CD015517. doi: 10.1002/14651858.CD015517.

本文引用的文献

Non-Hospitalized Long COVID Patients Exhibit Reduced Retinal Capillary Perfusion: A Prospective Cohort Study.

J Imaging. 2025 Feb 17;11(2):62. doi: 10.3390/jimaging11020062.

Author Correction: Profibrotic monocyte-derived alveolar macrophages are expanded in patients with persistent respiratory symptoms and radiographic abnormalities after COVID-19.

Nat Immunol. 2025 Feb;26(2):323. doi: 10.1038/s41590-025-02076-z.

Neurologic Manifestations of Long COVID Disproportionately Affect Young and Middle-Age Adults.

Ann Neurol. 2025 Feb;97(2):369-383. doi: 10.1002/ana.27128. Epub 2024 Nov 22.

Active Surveillance or Watchful Waiting for Intermediate-Risk Prostate Cancer, 2010-2020.

JAMA. 2024 Dec 17;332(23):2033-2036. doi: 10.1001/jama.2024.20580.

Mechanisms of long COVID and the path toward therapeutics.

Cell. 2024 Oct 3;187(20):5500-5529. doi: 10.1016/j.cell.2024.07.054. Epub 2024 Sep 25.

Long COVID science, research and policy.

Nat Med. 2024 Aug;30(8):2148-2164. doi: 10.1038/s41591-024-03173-6. Epub 2024 Aug 9.

Long COVID as a disease of accelerated biological aging: An opportunity to translate geroscience interventions.

Ageing Res Rev. 2024 Aug;99:102400. doi: 10.1016/j.arr.2024.102400. Epub 2024 Jun 28.

Long COVID and its association with neurodegenerative diseases: pathogenesis, neuroimaging, and treatment.

Front Neurol. 2024 Apr 4;15:1367974. doi: 10.3389/fneur.2024.1367974. eCollection 2024.

Plasma proteomics show altered inflammatory and mitochondrial proteins in patients with neurologic symptoms of post-acute sequelae of SARS-CoV-2 infection.

Brain Behav Immun. 2023 Nov;114:462-474. doi: 10.1016/j.bbi.2023.08.022. Epub 2023 Sep 11.

Long COVID and older people.

Lancet Healthy Longev. 2022 Dec;3(12):e849-e854. doi: 10.1016/S2666-7568(22)00245-8.