O'Connor Lauren F, Resnik Jenna B, Byrne Morgan, Houston Patricia E, Simmens Sam, Castel Amanda D, Rana Sohail, Monroe Anne K
Department of Epidemiology, Milken Institute School of Public Health, George Washington University, Washington, District of Columbia, USA.
Department of Pediatrics and Child Health, College of Medicine, Howard University, Washington, District of Columbia, USA.
J Int Assoc Provid AIDS Care. 2025 Jan-Dec;24:23259582251370561. doi: 10.1177/23259582251370561. Epub 2025 Aug 29.
ObjectivesThere is a high prevalence of internalized stigma among people with HIV (PWH) and it is possible that factors associated with stigma differ by gender. Therefore, we evaluated whether gender is an effect modifier of the association between covariates and internalized stigma among 694 PWH.MethodsLinear regression with interaction terms between covariates and gender was used to evaluate significant associations and test for interactions.ResultsWe found a 10-year increase in age was associated with lower stigma among women (β (95% CI): -0.20 (-0.30, -0.10)) but not among men (β = 0). Generalized anxiety disorder (GAD) was associated with higher stigma (GAD & GAD-squared β (95% CI): 0.12 (0.08, 0.187), -0.004 (-0.006, -0.001)) and an increased time since HIV diagnosis was associated with lower stigma (β (95% CI): -0.20 (-0.30, -0.10)).ConclusionsGender-specific interventions should be developed to account for the differences in the association between age and stigma across genders.
目的
艾滋病毒感染者(PWH)中内化耻辱感的患病率很高,并且与耻辱感相关的因素可能因性别而异。因此,我们评估了在694名艾滋病毒感染者中,性别是否是协变量与内化耻辱感之间关联的效应修饰因素。
方法
使用协变量与性别之间的交互项进行线性回归,以评估显著关联并检验交互作用。
结果
我们发现,年龄每增加10岁,女性的耻辱感会降低(β(95%置信区间):-0.20(-0.30,-0.10)),而男性则无此关联(β = 0)。广泛性焦虑症(GAD)与更高的耻辱感相关(GAD及GAD平方β(95%置信区间):0.12(0.08,0.187),-0.004(-0.006,-0.001)),自艾滋病毒诊断以来时间增加与耻辱感降低相关(β(95%置信区间):-0.20(-0.30,-0.10))。
结论
应制定针对性别的干预措施,以考虑不同性别在年龄与耻辱感关联方面的差异。