异基因干细胞移植中的“抗生素悖论” - Suppr

"The antibiotic paradox" in allogeneic stem cell transplantation.

作者信息

Weber Daniela, Meedt Elisabeth, Ghimire Sakhila, Hiergeist Andreas, Kern Michael A G, Höpting Matthias, Thiele Orberg Erik, Shaikh Haroon, Beilhack Andreas, Wolff Daniel, Edinger Matthias, Herr Wolfgang, Gessner Andre, Poeck Hendrik, Holler Ernst

机构信息

Clinic and Polyclinic for Internal Medicine III, University Hospital Regensburg, Regensburg, Germany.

Institute of Micrbiology and Hygiene, University Hospital Regensburg, Regensburg, Germany.

出版信息

Bone Marrow Transplant. 2025 Sep 4. doi: 10.1038/s41409-025-02706-y.

DOI:10.1038/s41409-025-02706-y

PMID:40903551

Abstract

摘要

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本文引用的文献

The antibiotic de-escalation strategy in patients with multidrug-resistant bacterial colonization after allogeneic stem cell transplantation.

Front Microbiol. 2025 Jan 3;15:1487617. doi: 10.3389/fmicb.2024.1487617. eCollection 2024.

Bacteria and bacteriophage consortia are associated with protective intestinal metabolites in patients receiving stem cell transplantation.

Nat Cancer. 2024 Jan;5(1):187-208. doi: 10.1038/s43018-023-00669-x. Epub 2024 Jan 3.

Restrictive Versus Permissive Use of Broad-spectrum Antibiotics in Patients Receiving Allogeneic Stem Cell Transplantation and With Early Fever Due to Cytokine Release Syndrome: Evidence for Beneficial Microbiota Protection Without Increase in Infectious Complications.

Clin Infect Dis. 2023 Nov 17;77(10):1432-1439. doi: 10.1093/cid/ciad389.

High-resolution analyses of associations between medications, microbiome, and mortality in cancer patients.

Cell. 2023 Jun 8;186(12):2705-2718.e17. doi: 10.1016/j.cell.2023.05.007.

Cancer and the Microbiome-Influence of the Commensal Microbiota on Cancer, Immune Responses, and Immunotherapy.

Gastroenterology. 2021 Jan;160(2):600-613. doi: 10.1053/j.gastro.2020.11.041. Epub 2020 Nov 28.

Microbiota as Predictor of Mortality in Allogeneic Hematopoietic-Cell Transplantation.

N Engl J Med. 2020 Feb 27;382(9):822-834. doi: 10.1056/NEJMoa1900623.

Metabolomics analysis of human acute graft-versus-host disease reveals changes in host and microbiota-derived metabolites.

Nat Commun. 2019 Dec 13;10(1):5695. doi: 10.1038/s41467-019-13498-3.

Early discontinuation of antibiotics for febrile neutropenia versus continuation until neutropenia resolution in people with cancer.

Cochrane Database Syst Rev. 2019 Jan 3;1(1):CD012184. doi: 10.1002/14651858.CD012184.pub2.

Neutrophil granulocytes recruited upon translocation of intestinal bacteria enhance graft-versus-host disease via tissue damage.

Nat Med. 2014 Jun;20(6):648-54. doi: 10.1038/nm.3517. Epub 2014 May 18.

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"The antibiotic paradox" in allogeneic stem cell transplantation.

作者信息

机构信息

Clinic and Polyclinic for Internal Medicine III, University Hospital Regensburg, Regensburg, Germany.

Institute of Micrbiology and Hygiene, University Hospital Regensburg, Regensburg, Germany.

出版信息

Bone Marrow Transplant. 2025 Sep 4. doi: 10.1038/s41409-025-02706-y.

DOI:10.1038/s41409-025-02706-y

PMID:40903551

Abstract

摘要

"The antibiotic paradox" in allogeneic stem cell transplantation.

作者信息

机构信息

出版信息

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"The antibiotic paradox" in allogeneic stem cell transplantation.

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