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老年人用药依从性:潜在因素、干预措施及结果

Medication Non-adherence in Older Adults: Underlying Factors, Potential Interventions and Outcomes.

作者信息

Stanly Elstin Anbu Raj, Vilakkathala Rajesh, George Johnson

机构信息

Center for Evidence-Informed Decision Making, Prasanna School of Public Health, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.

Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.

出版信息

Drugs Aging. 2025 Sep 11. doi: 10.1007/s40266-025-01249-7.

Abstract

Polypharmacy is very common among older adults and is associated with poor health outcomes. This scoping review aimed to understand the underlying factors for poor medication taking by older patients and potential solutions to mitigate these risks. The ability to take medications and adherence are affected by various factors related to patients, treatments, health conditions and socio-demographics, healthcare providers and the healthcare systems. Educational and behavioural interventions are used alone or in combination for the optimisation medication use. Medication review and deprescribing, including regimen simplification, by trained practitioners has the potential to enhance patient safety and reduce healthcare costs. Engaging the patient and family may bring about additional benefits. Various technology-based interventions to promote self-efficacy are evolving and are used to support consumer self-management.

摘要

多重用药在老年人中非常普遍,且与不良健康结局相关。本综述旨在了解老年患者用药不佳的潜在因素以及降低这些风险的潜在解决方案。用药能力和依从性受到与患者、治疗、健康状况、社会人口统计学、医疗服务提供者及医疗系统相关的各种因素影响。教育和行为干预单独或联合使用以优化药物使用。由经过培训的从业者进行药物审查和减药(包括简化用药方案)有可能提高患者安全性并降低医疗成本。让患者及其家人参与可能会带来额外益处。各种基于技术的促进自我效能的干预措施正在不断发展,并用于支持消费者自我管理。

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