Horie Shintaro, Yoshida Takeshi, Ohno-Matsui Kyoko
Department of Ophthalmology and Visual Science, Institute of Science Tokyo, Tokyo 113-8519, Japan.
Department of Ophthalmology and Visual Science, Department of Advanced Ophthalmic Imaging, Institute of Science Tokyo, Tokyo 113-8519, Japan.
Bioengineering (Basel). 2025 Sep 7;12(9):962. doi: 10.3390/bioengineering12090962.
Optical coherence tomography (OCT) is an indispensable tool in modern ophthalmology, where it is used in prior examinations, among various instruments, to assess macular or vitreoretinal diseases. Pathological macular/retinal conditions are almost always examined and evaluated with OCT before and after treatment. Vitreoretinal surgery is one of the most effective treatment options for vitreoretinal diseases. OCT data collected during the treatment of these diseases has accumulated, leading to the reporting of a variety of novel biomarkers and valuable findings related to OCT usage. Recent substantial developments in technology have brought ultra-high-resolution spectral domain/swept source OCT, ultra-widefield OCT, and OCT angiography into the retinal clinic. Here, we review the basic development of the instrument and general applications of OCT in ophthalmology. Subsequently, we provide up-to-date OCT topics based on observations in vitreoretinal surgery.
光学相干断层扫描(OCT)是现代眼科不可或缺的工具,在各种仪器中,它被用于先前的检查,以评估黄斑或玻璃体视网膜疾病。病理性黄斑/视网膜疾病几乎总是在治疗前后通过OCT进行检查和评估。玻璃体视网膜手术是治疗玻璃体视网膜疾病最有效的选择之一。在这些疾病的治疗过程中收集的OCT数据不断积累,导致报告了各种与OCT使用相关的新型生物标志物和有价值的发现。最近技术的重大发展已将超高分辨率光谱域/扫频源OCT、超广角OCT和OCT血管造影引入视网膜临床。在此,我们回顾该仪器的基本发展情况以及OCT在眼科的一般应用。随后,我们根据玻璃体视网膜手术中的观察结果提供最新的OCT主题。