Brauman J, Brauman H, van Camp B, Mathieu J
Acta Radiol Diagn (Stockh). 1977 Nov;18(6):715-20. doi: 10.1177/028418517701800616.
No modification of plasma or serum viscosity was observed after in vitro addition of ioglycamide in a series of 160 healthy subjects and 1 467 patients including 33 cases of IgM paraproteinemia, 20 with Waldenström's disease. The labelled contrast medium never bound to paraproteins. These results are contradictory to the statements in the literature, that plasma gel formation occurs in Waldenström's disease.
在一系列160名健康受试者和1467名患者(包括33例IgM副蛋白血症患者、20例华氏巨球蛋白血症患者)中,体外添加碘海酰胺后未观察到血浆或血清粘度的改变。标记的造影剂从未与副蛋白结合。这些结果与文献中关于华氏巨球蛋白血症中发生血浆凝胶形成的说法相矛盾。