氯霉素特异性抗体。3. 针对一种抗原上不同决定簇的抗体衰减率差异。
Chloramphenicol-specific antibody. 3. Differential antibody decay rates to separate determinants on one antigen.
作者信息
Hamburger R N, Douglass J H
出版信息
Immunology. 1969 Oct;17(4):593-7.
Abstract
In rabbits, peak titres to repeated immunization with chloramphenicol bound to bovine γ-globulin (CAP—BGG) appear on the 4th to 7th day for the BGG part of the antigen, but not until the 9th to 12th day for CAP. Similarly the antibody to CAP declines in titre much more rapidly than the antibody to the BGG and 4–6 weeks later anti-CAP antibody is no longer detectable while the anti-BGG antibody is still found in high titre.
摘要
在兔子中，用与牛γ球蛋白结合的氯霉素（CAP - BGG）进行重复免疫时，针对抗原中BGG部分的峰值滴度出现在第4至7天，而针对CAP的峰值滴度直到第9至12天才出现。同样，针对CAP的抗体滴度下降速度比针对BGG的抗体快得多，4至6周后，抗CAP抗体不再能检测到，而抗BGG抗体仍以高滴度存在。
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