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增殖性肾小球肾炎及肾移植后纤维蛋白原相关物质、补体和免疫球蛋白的尿排泄情况。

Urinary excretion of fibrinogen-related materials, complement, and immunoglobulins in proliferative glomerulonephritis and after renal transplantation.

作者信息

Hoq M S, Anderton J L, Cunningham M, Cash J D

出版信息

Br Med J. 1974 Jun 8;2(5918):535-8. doi: 10.1136/bmj.2.5918.535.

Abstract

Using a radial immunodiffusion technique we measured the urinary concentration of material related to complement (C3), IgM, and IgG along with fibrin-fibrinogen degradation products and heterophile (sheep) haemagglutinins in 15 patients with proliferative glomerulonephritis and in 10 patients after renal transplantation. There was a significant correlation between all variables measured, and serial studies showed that with the exception of IgG-related materials potentially useful information could be obtained on the detection of rejection and the response to treatment in both conditions. The significance of these observations is discussed.

摘要

我们采用放射免疫扩散技术,测定了15例增殖性肾小球肾炎患者和10例肾移植患者尿液中与补体(C3)、IgM、IgG相关物质的浓度,以及纤维蛋白 - 纤维蛋白原降解产物和嗜异性(绵羊)血凝素的浓度。所测的所有变量之间存在显著相关性,系列研究表明,除了与IgG相关的物质外,在这两种情况下,均可通过检测获得有关排斥反应及治疗反应的潜在有用信息。本文讨论了这些观察结果的意义。

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引用本文的文献

1
Urinary excretion of C3 antigen in glomerulonephritis.
Br Med J. 1974 Oct 5;4(5935):21-3. doi: 10.1136/bmj.4.5935.21.
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Significance of urinary C3 excretion in glomerulonephritis.
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Urinary excretion of factor VIII after renal transplantation.
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Raised urinary fibrin-degradation products, complement, and IgG during an influenza-like illness.
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