Czernobilsky B, Morris W J
Obstet Gynecol. 1979 Mar;53(3):318-23.
One hundred ninety-four cases of ovarian endometriosis, encountered during a 3-year period, were studied. In addition to endometrial-type epithelium and stroma that were present in each of these cases, oviduct-type epithelium was demonstrated in 26, papillary epithelial-lined projections in 7, and hobnail cells in 36 patients. Forty-three cases showed reactive epithelial changes, probably due to inflammation and regeneration. There were 4 cases of adenomatous hyperplasia. Severe epithelial atypism was seen in 7 patients (3.6%), 1 in conjunction with adenomatous hyperplasia. Although the areas of severe epithelial atypism in ovarian endometriosis may be of reactive origin, one must also consider the possibility that in some instances these atypical changes may constitute a neoplastic potential.
对三年间遇到的194例卵巢子宫内膜异位症病例进行了研究。除了每例病例中均存在的子宫内膜样上皮和间质外，26例显示有输卵管样上皮，7例有乳头样上皮衬里的突起，36例有鞋钉样细胞。43例显示反应性上皮改变，可能是由于炎症和再生所致。有4例腺瘤样增生。7例患者（3.6%）出现严重上皮异型性，其中1例与腺瘤样增生并存。虽然卵巢子宫内膜异位症中严重上皮异型性区域可能是反应性起源，但也必须考虑在某些情况下这些非典型改变可能具有肿瘤潜能的可能性。
