[芳基磺酰肼及其衍生物的降血糖活性]
[Hypoglycemic activity of aromatic sulfohydrazides and their derivatives].
作者信息
Chernykh V P, Makurina V I, Dzhan-Temirova T S, Petiunin P A, Khaleeva L D
出版信息
Farmakol Toksikol. 1979 May-Jun;42(3):285-7.
PMID:446713
Abstract
Tests on rabbits revealed the aromatic sulfohydrazides and their derivatives to display hypoglycemic action. A number of compounds superior to butamide by their sugar-lowering action and of low toxicity were discovered. The relationship between the chemical structure of the study substances and their hypoglycemic action is discussed.
摘要
对兔子的试验表明，芳基磺酰肼及其衍生物具有降血糖作用。发现了许多在降血糖作用方面优于丁酰胺且毒性低的化合物。讨论了所研究物质的化学结构与其降血糖作用之间的关系。
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