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一头装有人工心脏的小牛的六个月生存期。

Six-month survival of a calf with an artificial heart.

作者信息

Lawson J H, Fukumasu H, Olsen D B, Jarvik R K, Kessler T R, Coleman D, Pons A B, Blaylock R, Kolff W J

出版信息

J Thorac Cardiovasc Surg. 1979 Jul;78(1):150-6.

PMID:449382
Abstract

A pneumatically powered artificial heart, constructed primarily from a polyurethane, was implanted in the chest of a calf and supported the calf for more than 6 months. The heart, which was designed to fit in the chest of a 90 kilogram calf, was able to suppor the animal when it weighed 180 kilograms. During the first 105 days the calf remained strong and healthy. The animal grew progressively weaker after day 106, and by day 160 right heart failure became apparent. The principal cause of the right heart failure was an obstructive growth between the right atrium and the right ventricle. An attempt to correct the problem on day 184 with an artificial heart resulted in the animal's death.

摘要

一个主要由聚氨酯制成的气动人工心脏被植入一头小牛的胸腔,并维持这头小牛生命超过6个月。这个设计用于适配一头90公斤小牛胸腔的心脏,在小牛体重达到180公斤时仍能维持其生命。在最初的105天里,小牛一直强壮健康。106天后,这头小牛逐渐变得虚弱,到第160天,右心衰竭明显显现。右心衰竭的主要原因是右心房和右心室之间出现阻塞性增生。在第184天尝试用人工心脏纠正这个问题,结果导致了小牛的死亡。

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