Ramsay R C, Kinyoun J L, Hill C W, Aturaliya U P, Knobloch W H
Am J Ophthalmol. 1979 Jul;88(1):32-6. doi: 10.1016/0002-9394(79)90748-7.
A 41-year-old man had a 6 x 6 x 5-disk diameter amelanotic tumor in the posterior fundus. The clinical and fluorescein angiographic appearance suggested a benign retinal vascular tumor, although amelanotic choroidal melanoma and retinoblastoma were diagnostic possibilities. An incisional 48-hour radioactive phosphorus (32P) uptake test was performed and the result showed an increased uptake over the tumor mass of 100% as compared to the control quadrants. The globe was enucleated and the pathologic diagnosis was isolated astrocytic glioma of the retina with minimal, if any, malignant potential. The highly developed vascular system of the tumor probably contributed to the false-positive test result.
一名41岁男性眼底后部有一个直径为6×6×5视盘大小的无色素肿瘤。临床及荧光素血管造影表现提示为良性视网膜血管肿瘤,不过无色素脉络膜黑色素瘤和视网膜母细胞瘤也在鉴别诊断范围内。进行了切开活检48小时放射性磷(³²P)摄取试验,结果显示肿瘤块的摄取量比对照象限增加了100%。眼球被摘除,病理诊断为孤立性视网膜星形细胞胶质瘤,恶性潜能极小(即便有也微乎其微)。肿瘤高度发达的血管系统可能导致了假阳性的检查结果。