去氢依米丁肾上腺素能神经元阻断作用的某些特征。
Some characteristics of the adrenergic neurone blocking action of dehydroemetine.
作者信息
Gulati O D, Makol R, Shah D S
出版信息
Br J Pharmacol. 1973 Jun;48(2):314-7. doi: 10.1111/j.1476-5381.1973.tb06918.x.
Abstract
The uptake of dehydroemetine by adrenergic neurones was studied indirectly by testing the ability of various procedures to prevent or reverse adrenergic neurone blockade in the periarterially stimulated rabbit isolated ileum. Adrenergic neurone blockade was prevented but not reversed by equilibration with dehydroemetine at low temperature (0 degrees C), in the absence of sodium or in the presence of tetrodotoxin. Noradrenaline, cocaine, potassium deprivation and potassium excess did not modify the adrenergic neurone blocking action of dehydroemetine.
摘要
通过测试各种方法预防或逆转兔离体回肠动脉周围刺激引起的肾上腺素能神经元阻滞的能力，间接研究了脱氢吐根碱被肾上腺素能神经元的摄取情况。在低温（0℃）、无钠或有河豚毒素存在的情况下，用脱氢吐根碱平衡可预防但不能逆转肾上腺素能神经元阻滞。去甲肾上腺素、可卡因、钾缺乏和钾过量均未改变脱氢吐根碱的肾上腺素能神经元阻滞作用。
相似文献
1
Some characteristics of the adrenergic neurone blocking action of dehydroemetine.去氢依米丁肾上腺素能神经元阻断作用的某些特征。
Br J Pharmacol. 1973 Jun;48(2):314-7. doi: 10.1111/j.1476-5381.1973.tb06918.x.
2
Factors affecting the action of guanethidine on adrenergic neurones.影响胍乙啶对肾上腺素能神经元作用的因素。
Br J Pharmacol. 1971 Jul;42(3):352-63. doi: 10.1111/j.1476-5381.1971.tb07119.x.
3
The relation between the adrenergic neurone-blocking and noradrenaline-depleting actions of some guanidine derivatives.某些胍衍生物的肾上腺素能神经元阻断作用与去甲肾上腺素耗竭作用之间的关系。
Br J Pharmacol. 1974 Jun;51(2):237-47. doi: 10.1111/j.1476-5381.1974.tb09653.x.
4
Adrenergic neuron blocking action of dehydroemetine.去氢依米丁的肾上腺素能神经元阻断作用。
J Pharm Pharmacol. 1970 Oct;22(10):787. doi: 10.1111/j.2042-7158.1970.tb08434.x.
5
Mechanism of the antagonism between guanethidine and dexamphetamine.胍乙啶与右旋苯丙胺之间的拮抗作用机制。
Br J Pharmacol. 1969 Mar;35(3):563-72. doi: 10.1111/j.1476-5381.1969.tb08297.x.
6
The interaction between desmethylimipramine and guanethidine on the rabbit ileum. The importance of the noradrenaline uptake process in the reversal of guanethidine-induced adrenergic neurone blockade.去甲丙咪嗪与胍乙啶对兔回肠的相互作用。去甲肾上腺素摄取过程在胍乙啶诱导的肾上腺素能神经元阻滞逆转中的重要性。
Arch Int Pharmacodyn Ther. 1972 Aug;198(2):385-91.
7
Effect of neuronal uptake inhibitors on the adrenergic-neuron blockade produced by guanethidine in rabbit vas deferens.神经元摄取抑制剂对胍乙啶在兔输精管中产生的肾上腺素能神经元阻滞作用的影响。
Can J Physiol Pharmacol. 1977 Jun;55(3):609-14. doi: 10.1139/y77-084.
8
Adrenergic neurone blocking activity of some new guanidine derivatives.某些新型胍衍生物的肾上腺素能神经元阻断活性
Arch Int Pharmacodyn Ther. 1967 Dec;170(2):287-96.
9
Blockade of adrenergic and cholinergic transmissions by emetine.依米丁对肾上腺素能和胆碱能传递的阻断作用。
Br J Pharmacol Chemother. 1966 Nov;28(2):228-37. doi: 10.1111/j.1476-5381.1966.tb01889.x.
10
Inhibition by adrenergic neurone blocking agents of the relaxation induced by BRL 38227 in vascular, intestinal and uterine smooth muscle.肾上腺素能神经元阻断剂对BRL 38227诱导的血管、肠道和子宫平滑肌舒张的抑制作用。
Br J Pharmacol. 1992 Oct;107(2):288-95. doi: 10.1111/j.1476-5381.1992.tb12740.x.
本文引用的文献
1
On the nature of inhibition in the intestine.论肠道抑制的本质。
J Physiol. 1930 Sep 18;70(2):145-57. doi: 10.1113/jphysiol.1930.sp002683.
2
INTERACTION OF GUANETHIDINE WITH ADRENERGIC NEURONS.胍乙啶与肾上腺素能神经元的相互作用。
J Pharmacol Exp Ther. 1965 Mar;147:303-12.
3
Effect of sympathomimetic amines on the blocking action of guanethidine, bretylium and xylocholine.拟交感胺对胍乙啶、溴苄铵和樟柳碱阻断作用的影响。
Br J Pharmacol Chemother. 1962 Apr;18(2):421-39. doi: 10.1111/j.1476-5381.1962.tb01421.x.
4
Factors affecting the action of guanethidine on adrenergic neurones.影响胍乙啶对肾上腺素能神经元作用的因素。
Br J Pharmacol. 1971 Jul;42(3):352-63. doi: 10.1111/j.1476-5381.1971.tb07119.x.
5
Tetrodotoxin, saxitoxin and their significance in the study of excitation phenomena.河豚毒素、石房蛤毒素及其在兴奋现象研究中的意义。
Pharmacol Rev. 1966 Jun;18(2):997-1049.
6
The effect of dehydroemetine on isolated guinea-pig atria.去氢吐根碱对离体豚鼠心房的作用。
Br J Pharmacol. 1972 Apr;44(4):723-31. doi: 10.1111/j.1476-5381.1972.tb07310.x.
7
Pharmacodynamic effects of dehydroemetine.
J Pharm Pharmacol. 1972 Jan;24(1):32-9. doi: 10.1111/j.2042-7158.1972.tb08861.x.
8
Blockade of adrenergic transmission by dehydroemetine.去氢依米丁对肾上腺素能传递的阻断作用。
J Pharm Pharmacol. 1970 Dec;22(12):938-9. doi: 10.1111/j.2042-7158.1970.tb08477.x.
9
Cortical stimulation in rabbits by fenfluramine is probably due to an unusual metabolite.氟苯丙胺对兔子的皮层刺激可能归因于一种特殊的代谢产物。
J Pharm Pharmacol. 1970 Oct;22(10):786-7. doi: 10.1111/j.2042-7158.1970.tb08433.x.
10
Subcellular distribution of [3H]amphetamine and [3H]guanethidine and their interaction with adrenergic neurons.[3H]苯丙胺和[3H]胍乙啶的亚细胞分布及其与肾上腺素能神经元的相互作用。
J Pharm Pharmacol. 1968 Aug;20(8):585-94. doi: 10.1111/j.2042-7158.1968.tb09818.x.
Zotero 插件