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尼日利亚糖尿病与传染性肝炎流行相关。

Diabetes mellitus associated with epidemic of infectious hepatitis in Nigeria.

作者信息

Adi F C

出版信息

Br Med J. 1974 Feb 2;1(5900):183-5. doi: 10.1136/bmj.1.5900.183.

Abstract

This report concerns nine cases of diabetes mellitus associated with infectious hepatitis, an epidemic of which swept through eastern Nigeria between 1970 and 1972. All the patients showed the classical symptoms and signs of diabetes. They quickly responded to treatment, and after a few months the diabetes completely disappeared. Corticosteroid-glucose tolerance tests in four patients 12 to 30 months after the remission of their diabetes were normal. Contact with the remaining five patients had been lost a few months after clinical remission of their diabetes. The infectious hepatitis virus may have damaged pancreatic islet cells to cause an acute remittant form of diabetes mellitus.

摘要

本报告涉及9例与传染性肝炎相关的糖尿病病例,1970年至1972年期间,一场传染性肝炎疫情席卷了尼日利亚东部。所有患者均表现出糖尿病的典型症状和体征。他们对治疗反应迅速,几个月后糖尿病完全消失。4例患者在糖尿病缓解后12至30个月进行的皮质类固醇-葡萄糖耐量试验结果正常。其余5例患者在糖尿病临床缓解几个月后失去了联系。传染性肝炎病毒可能损害了胰岛细胞,从而导致急性缓解型糖尿病。

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本文引用的文献

2
Mumps followed by diabetes.
Lancet. 1962 Jun 30;1(7244):1381. doi: 10.1016/s0140-6736(62)92490-x.
4
An approach to the prediction of diabetes mellitus by modification of the glucose tolerance test with cortisone.
Diabetes. 1954 Jul-Aug;3(4):296-302; discussion, 302-4. doi: 10.2337/diab.3.4.296.

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