辐射诱发的染色体异常在放射防护中的意义。
The significance of radiation-induced chromosome abnormalities in radiological protection.
作者信息
Dolphin G W, Lloyd D C
出版信息
J Med Genet. 1974 Jun;11(2):181-9. doi: 10.1136/jmg.11.2.181.
Abstract
A brief review is given of the production and analysis of chromosome aberrations induced by ionizing radiation. The various tissues in which it is possible to demonstrate aberrations are noted and particular emphasis is laid on the culture of peripheral blood lymphocytes. Some examples of recent applications of the technique are described. These are in the determination of suspected overdoses to radiation workers, in estimating doses to radiotherapy patients, and investigating the depth/biological profile for a negative π meson beam.
摘要
本文简要回顾了电离辐射诱导的染色体畸变的产生与分析。文中指出了能够检测到畸变的各种组织，并特别强调了外周血淋巴细胞培养。还描述了该技术近期应用的一些实例，包括确定辐射工作人员疑似过量照射剂量、估算放疗患者所受剂量，以及研究负π介子束的深度/生物学特性。
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