Gerbode F, Kerth W J, Hill J D, Banerjee S, Marcelletti C
Thorax. 1974 May;29(3):282-6. doi: 10.1136/thx.29.3.282.
, , 282-286. Operative results in 45 patients with symptomatic left ventricular asynergy are reviewed. The main symptoms were congestive heart failure in 77·7%, angina in 31·1%, arrhythmias in 11·1%, and systemic thromboembolism in 2·2% of the patients. All patients had left heart catheterization, 40 had left ventricular angiography, and 27 had selective coronary arteriography. The last myocardial infarction occurred within three months preoperatively in 15 patients and more than 13 months prior to surgery in 27 patients. The cardiac index was 1·5 1/m/min or less in six patients and the left ventricular end diastolic (LVED) pressure was 25 mmHg or higher in 15 patients. All patients were operated upon electively with the use of cardiopulmonary bypass. Excision of the left ventricular aneurysm was performed in 39 cases and plication in six. The immediate survival rate was 66·6%. The lowest mortality rate was among patients with angina (12·5%) and the highest in those with association of congestive heart failure and angina (66·6%). The mortality rates among patients with recent or old myocardial infarction were 46·6 and 22·2% respectively. One of the six patients with a cardiac index of 1·5 1/m/min or less and seven of the 15 patients with LVED pressure of 25 mmHg or higher were discharged from hospital. It is concluded that ventricular aneurysmectomy has to be considered an elective procedure in order to obtain predictable results and that ideal indications for operation are angina or congestive heart failure refractory to medical treatment, associated with acceptable haemodynamics, a cardiac index of 2·0 1/m/min or higher, and a LVED pressure below 25 mmHg.
回顾了45例有症状的左心室协同失调患者的手术结果。主要症状为:77.7%的患者有充血性心力衰竭,31.1%的患者有心绞痛,11.1%的患者有心律失常,2.2%的患者有系统性血栓栓塞。所有患者均进行了左心导管检查,40例进行了左心室造影,27例进行了选择性冠状动脉造影。15例患者术前三个月内发生最后一次心肌梗死,27例患者术前13个月以上发生最后一次心肌梗死。6例患者心脏指数为1.5升/米/分钟或更低,15例患者左心室舒张末期(LVED)压力为25毫米汞柱或更高。所有患者均在体外循环下择期手术。39例患者进行了左心室动脉瘤切除术,6例进行了折叠术。即时生存率为66.6%。死亡率最低的是心绞痛患者(12.5%),最高的是充血性心力衰竭合并心绞痛患者(66.6%)。近期或陈旧性心肌梗死患者的死亡率分别为46.6%和22.2%。6例心脏指数为1.5升/米/分钟或更低的患者中有1例,15例LVED压力为25毫米汞柱或更高的患者中有7例出院。结论是,为了获得可预测的结果,心室动脉瘤切除术必须被视为一种择期手术,理想的手术适应症是药物治疗无效的心绞痛或充血性心力衰竭,伴有可接受的血流动力学,心脏指数为2.0升/米/分钟或更高,LVED压力低于25毫米汞柱。