Fisher G L, Pfaffmann C, Brown E
Science. 1965 Oct 22;150(3695):506-7. doi: 10.1126/science.150.3695.506.
In a taste-preference comparison of sweetening agents, men reacted positively to two nonnutritive sweeteners, dulcin and sodium saccharin; rats preferred only saccharin and squirrel monkeys, only dulcin.