Wakushima T, Yamanishi Y, Hirayama C
Radioisotopes. 1979 Jul;28(7):437-40. doi: 10.3769/radioisotopes.28.7_437.
Serum levels of cholylglycines (CG) were determined by radioimmunoassay and that of total bile acids (TBA) by enzymatic method. In normal subjects, serum levels of CG, TBA and CG/TBA ratio were 0.6 +/- 0.4 micronM, 7 +/- 2 micronM and 0.08 +/- 0.06, respectively. They were increased markedly in acute hepatitis and moderately in chronic hepatitis and cirrhosis. Thus, measurement of serum CG as compared with serum TBA appears to be a sensitive liver test.
采用放射免疫分析法测定血清甘氨胆酸(CG)水平,用酶法测定总胆汁酸(TBA)水平。在正常受试者中,血清CG、TBA水平及CG/TBA比值分别为0.6±0.4微摩尔/升、7±2微摩尔/升和0.08±0.06。在急性肝炎时它们显著升高,在慢性肝炎和肝硬化时中度升高。因此,与血清TBA相比,血清CG的测定似乎是一种敏感的肝功能检测方法。