Inhibition by lymphocyte nuclei of DNA and RNA synthesis in stimulated lymphocytes and leukaemic cells.
作者信息
Pegrum G D, Thompson E
出版信息
Br J Exp Pathol. 1971 Oct;52(5):560-4.
Abstract
Chromatin material in the form of intact bald lymphocyte nuclei was found to inhibit DNA and RNA synthesis in isologous cells previously stimulated with Phytohaemagglutinin (PHA) especially in 6 day cultures. These bald nuclear complexes produced a reduction in the DNA and RNA synthesis occurring in allogenic leukaemic cells.
摘要
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Inhibition by lymphocyte nuclei of DNA and RNA synthesis in stimulated lymphocytes and leukaemic cells.
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