粗糙脉孢菌将组氨酸转化为肌肽。
Conversion of histidine to hercynine by Neurospora crassa.
作者信息
Reinhold V N, Ishikawa Y, Melville D B
出版信息
J Bacteriol. 1970 Mar;101(3):881-4. doi: 10.1128/jb.101.3.881-884.1970.
Abstract
Cell-free extracts of Neurospora crassa mycelium catalyze the methylation of l-histidine to form hercynine (histidine betaine). The partially methylated compounds, alpha-N-methyl-l-histidine and alpha-N,N-dimethyl-l-histidine, are also methylated by the same enzyme preparation to form hercynine. All three methylation reactions are stimulated by the addition of S-adenosylmethionine.
摘要
粗糙脉孢菌菌丝体的无细胞提取物催化L-组氨酸甲基化形成肌肽（组氨酸甜菜碱）。部分甲基化的化合物，α-N-甲基-L-组氨酸和α-N，N-二甲基-L-组氨酸，也可被相同的酶制剂甲基化形成肌肽。所有这三种甲基化反应都因添加S-腺苷甲硫氨酸而受到刺激。
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本文引用的文献
1
BIOSYNTHESIS OF ERGOTHIONEINE AND HERCYNINE BY MYCOBACTERIA.分枝杆菌对麦角硫因和组氨酸三甲铵乙内酯的生物合成
J Bacteriol. 1964 Apr;87(4):852-62. doi: 10.1128/jb.87.4.852-862.1964.
2
The reaction sequence in ergothioneine biosynthesis: hercynine as an intermediate.麦角硫因生物合成中的反应序列：组氨酸三甲铵内盐作为中间体。
J Biol Chem. 1962 May;237:1615-8.
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Transmethylation in the biosynthesis of ergothionelne.麦角硫因生物合成中的转甲基作用。
J Biol Chem. 1959 May;234(5):1195-8.
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The biosynthesis of ergothioneine.麦角硫因的生物合成。
J Biol Chem. 1957 Feb;224(2):871-7.
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Ergothioneine in microorganisms.微生物中的麦角硫因。
J Biol Chem. 1956 Nov;223(1):9-17.
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Properties of a phosphatidylmonomethylethanolamine N-methyl-transferase from Neurospora crassa.来自粗糙脉孢菌的磷脂酰单甲基乙醇胺N-甲基转移酶的特性
Biochim Biophys Acta. 1967 Sep 12;146(1):111-9. doi: 10.1016/0005-2744(67)90077-0.
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Synthesis of alpha-N-methylated histidines.α-N-甲基化组氨酸的合成。
J Med Chem. 1968 Mar;11(2):258-60. doi: 10.1021/jm00308a014.
8
Biosynthesis of ergothioneine from endogenous hercynine in Mycobacterium smegmatis.耻垢分枝杆菌中内源性肌肽合成麦角硫因的过程。
J Bacteriol. 1968 Feb;95(2):340-4. doi: 10.1128/jb.95.2.340-344.1968.
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