卡介苗液体菌株和冻干菌株预防结核病效果的比较。
Comparison of the efficacy of liquid and freeze-dried strains of B.C.G. vaccine in preventing tuberculosis.
作者信息
Springett V H, Sutherland I
出版信息
Br Med J. 1970 Oct 17;4(5728):148-50. doi: 10.1136/bmj.4.5728.148.
Analysis of the tuberculosis notifications and the statistics of B.C.G. vaccinations among 13-year-old schoolchildren in Birmingham, England, between 1953 and 1969 shows that the Copenhagen strain of B.C.G. (liquid batches issued 1953-61) and the Glaxo Laboratories strain (freeze-dried batches issued 1962-68) were of similar high efficacy in the prevention of tuberculosis. The method of analysis could be used for the surveillance of the protective efficacy of B.C.G. vaccine in other population groups where it is used routinely but not universally.
对1953年至1969年间英国伯明翰13岁学童的结核病通报情况及卡介苗接种统计数据进行分析后发现，哥本哈根株卡介苗（1953 - 1961年发放的液体批次）和葛兰素实验室株（1962 - 1968年发放的冻干批次）在预防结核病方面具有相似的高效性。该分析方法可用于监测卡介苗在其他常规但并非普遍使用的人群中的保护效果。
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