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巨噬细胞与淋巴细胞之间的抗原差异。

Antigenic differences between macrophages and lymphocytes.

作者信息

Marsman A W, van der Hart M, van Loghem J J

出版信息

Clin Exp Immunol. 1970 Jun;6(6):899-903.

Abstract

Antisera against guinea-pig lymphocytes and guinea-pig macrophages were prepared by injecting rabbits with purified blood lymphocytes or peritoneal macrophages. Both antisera contained antibodies of at least two different specificities, one reacting with an antigen common to lymphocytes and macrophages and one specific for either lymphocytes or macrophages. Opsonic adherence and phagocytosis of sensitized red cells by macrophages were inhibited by the anti-macrophage serum. The anti-lymphocyte serum showed no such inhibition, when previously absorbed with macrophages.

摘要

通过给兔子注射纯化的血液淋巴细胞或腹腔巨噬细胞,制备了抗豚鼠淋巴细胞和抗豚鼠巨噬细胞的抗血清。两种抗血清都含有至少两种不同特异性的抗体,一种与淋巴细胞和巨噬细胞共有的抗原发生反应,另一种对淋巴细胞或巨噬细胞具有特异性。巨噬细胞对致敏红细胞的调理吞噬作用被抗巨噬细胞血清所抑制。当抗淋巴细胞血清预先用巨噬细胞吸收后,未表现出这种抑制作用。

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