复方新诺明治疗急性布鲁氏菌病
Trimethoprim-sulphamethoxazole in acute brucellosis.
作者信息
Hassan A, Erian M M, Farid Z, Hathout S D, Sorensen K
出版信息
Br Med J. 1971 Jul 17;3(5767):159-60. doi: 10.1136/bmj.3.5767.159.
Abstract
Eight patients with proved brucella infection were treated with trimethoprim-sulphamethoxazole. The dose varied from two to four tablets given twice daily for three weeks. Clinical response was rapid and all patients were asymptomatic and afebrile within two to seven days of starting therapy. Three patients relapsed clinically and bacteriologically within three weeks of ending treatment. There were no side effects of the treatment. It is suggested that the treatment be continued for at least six weeks to prevent relapses.
摘要
八名确诊为布鲁氏菌感染的患者接受了甲氧苄啶-磺胺甲恶唑治疗。剂量为每日两次，每次两至四片，持续三周。临床反应迅速，所有患者在开始治疗后的两至七天内均无症状且无发热。三名患者在治疗结束后的三周内出现临床和细菌学复发。治疗无副作用。建议治疗至少持续六周以预防复发。
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