能否从动物实验数据预测抗精神病药物（强效镇静剂）的临床效果？IV. 一种改进的实验设计，用于测量抗精神病药物对大鼠中苯丙胺或阿扑吗啡诱导的“刻板行为”和“激动”的抑制作用。 - Suppr

Is it possible to predict the clinical effects of neuroleptic drugs (major tranquillizers) from animal data? IV. An improved experimental design for measuring the inhibitory effects of neuroleptic drugs on amphetamine-or apomorphine-induced "Cheroing" and "agitation" in rats.

作者信息

Janssen P A, Niemegeers C J, Schellekens K H, Lenaerts F M

出版信息

Arzneimittelforschung. 1967 Jul;17(7):841-54.

PMID:5632842

Abstract

摘要

相似文献

Is it possible to predict the clinical effects of neuroleptic drugs (major tranquillizers) from animal data? IV. An improved experimental design for measuring the inhibitory effects of neuroleptic drugs on amphetamine-or apomorphine-induced "Cheroing" and "agitation" in rats.

Arzneimittelforschung. 1967 Jul;17(7):841-54.

[Neuroleptic therapy of schizophrenia from pharmacological viewpoint].

Schweiz Med Wochenschr. 1969 Nov 15;99(46):1645-52 contd.

Studies of flavin-adenine dinucleotide-requiring enzymes and phenothiazines. 3. Inhibition kinetics with highly purified D-amino acid oxidase.

Biochem Pharmacol. 1967 May;16(5):803-12. doi: 10.1016/0006-2952(67)90053-6.

The influence of various neuroleptic drugs on noise escape response in rats.

Psychopharmacologia. 1970;18(3):249-59. doi: 10.1007/BF00412671.

Antagonistic activity of some phenothiazine derivatives against neurohumoral transmitters.

Jpn J Pharmacol. 1973 Jun;23(3):363-71. doi: 10.1254/jjp.23.363.

Some relationships concerning the chemical structure, hemolytic activity, and therapeutic potency of phenothiazines.

Biochem Pharmacol. 1966 Apr;15(4):501-4. doi: 10.1016/0006-2952(66)90260-7.

Potentiation and inhibition of the amphetamine stereotypy in rats by neuroleptics and other agents.

Arch Int Pharmacodyn Ther. 1972 Oct;199(2):289-301.

Phenothiazine depression of approach and avoidance behavior.

Psychopharmacologia. 1967;10(3):196-203. doi: 10.1007/BF00401381.

The relationship between the lipophilic nature of tricyclic neuroleptics and antidepressants, and histamine release.

Eur J Pharmacol. 1972 May;18(2):139-47. doi: 10.1016/0014-2999(72)90235-x.

[Activity of various neuroleptics after single repeated treatment in the mice submitted to the four plate test and the escape test].

C R Seances Soc Biol Fil. 1974;168(2-3):270-5.

引用本文的文献

Behavioural characterization of neuroleptic properties in the rodent.

Proc R Soc Med. 1977;70(Suppl 10):5-14. doi: 10.1177/0035915777070S1002.

Dopaminergic mechanisms in schizophrenia.

Proc R Soc Med. 1977;70(Suppl 10):1-4. doi: 10.1177/0035915777070S1001.

Features of central neurotransmission in animals in conditions of dietary magnesium deficiency and after its correction.

Neurosci Behav Physiol. 2009 Sep;39(7):645-53. doi: 10.1007/s11055-009-9182-y. Epub 2009 Jul 21.

Apomorphine and the dopamine hypothesis of schizophrenia: a dilemma?

J Psychiatry Neurosci. 2001 May;26(3):203-20.

Compulsive checking behavior of quinpirole-sensitized rats as an animal model of Obsessive-Compulsive Disorder(OCD): form and control.

BMC Neurosci. 2001;2:4. doi: 10.1186/1471-2202-2-4. Epub 2001 Apr 12.

SDZ PSD 958, a novel D1 receptor antagonist with potential limbic selectivity.

J Neural Transm (Vienna). 1996;103(3):261-76. doi: 10.1007/BF01271238.

Behavioural interactions between 5-hydroxytryptophan, neuroleptic agents and 5-HT receptor antagonists in modifying rodent responding to aversive situations.

Br J Pharmacol. 1995 Dec;116(7):2989-99. doi: 10.1111/j.1476-5381.1995.tb15954.x.

Survey on the pharmacodynamics of the new antipsychotic risperidone.

Psychopharmacology (Berl). 1994 Feb;114(1):9-23. doi: 10.1007/BF02245439.

Antagonism of the renal vasodilator activity of dopamine by metoclopramide.

Naunyn Schmiedebergs Arch Pharmacol. 1980 Nov;314(2):177-82. doi: 10.1007/BF00504535.

Differential effects of haloperidol and clozapine on attention.

Psychopharmacology (Berl). 1984;84(2):268-73. doi: 10.1007/BF00427457.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

Is it possible to predict the clinical effects of neuroleptic drugs (major tranquillizers) from animal data? IV. An improved experimental design for measuring the inhibitory effects of neuroleptic drugs on amphetamine-or apomorphine-induced "Cheroing" and "agitation" in rats.

作者信息

出版信息

相似文献

引用本文的文献

文献AI研究员

用中文搜PubMed

文档翻译

Suppr 超能文献

相似文献

引用本文的文献