碱性高铁血红素和含氮配体。

Alkaline haematin and nitrogenous ligands.

Gallagher W A, Elliott W B

Biochem J. 1968 Jun;108(1):131-6. doi: 10.1042/bj1080131.

Abstract

Pyridine reacts with alkaline haematin to form a dipyridine dihydroxy dimeric haematin in which there is no competition between pyridine and OH(-) for coordination positions on the iron of haematin. 2. Imidazole competes directly with OH(-) to form the monomeric imidazole parahaematin in alkaline media. 3. The monomeric imidazole parahaematin aggregates readily to form a species that is precipitated on standing. 4. A structure is proposed for the haematin-pyridine compound in alkaline media.

摘要

吡啶与碱性高铁血红素反应形成二吡啶二羟基二聚体高铁血红素，其中吡啶和OH(-)在高铁血红素铁的配位位置上不存在竞争。2. 在碱性介质中，咪唑直接与OH(-)竞争形成单体咪唑高铁血红素。3. 单体咪唑高铁血红素容易聚集形成一种静置时会沉淀的物质。4. 提出了碱性介质中高铁血红素 - 吡啶化合物的结构。