The suppression of experimental thyroiditis in the rat by heterologous anti-lymphocyte globulin.

The auto-allergic thyroiditis produced in rats by the injection of rat thyroglobulin in complete Freund's adjuvant can be suppressed by the administration of the IgG immunoglobulin fraction of heterologous (horse) anti-lymphocytic serum (ALS-IgG). ALS-IgG also suppressed the formation of circulating antibodies against rat thyroglobulin.