Irreversible enzyme inhibitors. 138. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 6-(p-aminomethylphenethyl)-- 2,4-diamino-5-(3,4-dichlorophenyl)pyrimidine with a terminal sulfonyl fluoride.
作者信息
Baker B R, Vermeulen N M
出版信息
J Med Chem. 1969 Jan;12(1):89-91. doi: 10.1021/jm00301a023.
PMID:5763048
Abstract
摘要
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Irreversible enzyme inhibitors. 138. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 6-(p-aminomethylphenethyl)-- 2,4-diamino-5-(3,4-dichlorophenyl)pyrimidine with a terminal sulfonyl fluoride.
J Med Chem. 1969 Jan;12(1):89-91. doi: 10.1021/jm00301a023.
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