无色杆菌对β-苯丙酸的代谢
The metabolism of beta-phenylpropionic acid by an Achromobacter.
作者信息
Dagley S, Chapman P J, Gibson D T
出版信息
Biochem J. 1965 Dec;97(3):643-50. doi: 10.1042/bj0970643.
Abstract
- When a species of Achromobacter grew with beta-phenylpropionate as carbon source, 2-hydroxy-beta-phenylpropionate and 2,3-dihydroxy-beta-phenylpropionate appeared in the growth medium. The concentrations of these compounds were maximal during exponential growth. 2. The cells contained an oxygenase that required Fe(2+) ions and cleaved the benzene nucleus between the adjacent carbon atoms that bear the side chain and one hydroxyl group of 2,3-dihydroxy-beta-phenylpropionate. 3. The ring-fission product, formed with the consumption of 1mol. of oxygen/mol. of substrate, was isolated and a chemical structure assigned. Sephadex-treated cell extracts converted 1mol. of this compound into 1mol. of 4-hydroxy-2-oxovalerate without oxygen consumption; succinic acid was also formed. 4. When Mn(2+) ions or Mg(2+) ions were added, dialysed extracts converted 4-hydroxy-2-oxovalerate into pyruvate and acetaldehyde, but the reaction did not proceed to completion.
摘要
- 当无色杆菌属的一个物种以β-苯丙酸作为碳源生长时，生长培养基中出现了2-羟基-β-苯丙酸和2,3-二羟基-β-苯丙酸。这些化合物的浓度在指数生长期间达到最大值。2. 细胞含有一种加氧酶，该酶需要Fe(2+)离子，并在带有侧链的相邻碳原子与2,3-二羟基-β-苯丙酸的一个羟基之间裂解苯环。3. 分离出以每摩尔底物消耗1摩尔氧气形成的开环产物，并确定了其化学结构。经葡聚糖凝胶处理的细胞提取物将1摩尔这种化合物转化为1摩尔4-羟基-2-氧代戊酸，且不消耗氧气；同时也形成了琥珀酸。4. 当加入Mn(2+)离子或Mg(2+)离子时，透析后的提取物将4-羟基-2-氧代戊酸转化为丙酮酸和乙醛，但反应未进行完全。
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本文引用的文献
1
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Biochem J. 1947;41(3):373-82. doi: 10.1042/bj0410373.
2
The bacterial oxidation of phenylacetic acid.苯乙酸的细菌氧化作用。
J Bacteriol. 1952 Mar;63(3):327-36. doi: 10.1128/jb.63.3.327-336.1952.
3
4
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5
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Biochem J. 1965 Apr;95(1):48-58. doi: 10.1042/bj0950048.
6
ON THE MECHANISM OF RING A CLEAVAGE IN THE DEGRADATION OF 9,10-SECO STEROIDS BY MICROORGANISMS.微生物对9,10-开环甾体降解中环A裂解的机制
J Am Chem Soc. 1965 Mar 20;87:1386-7. doi: 10.1021/ja01084a043.
7
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J Biol Chem. 1964 Jul;239:2204-11.
8
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Nature. 1964 May 23;202:775-8. doi: 10.1038/202775a0.
9
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10
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