Castro A, Dhindsa D S, Hoversland A S, Villa L, Rosenthiel C, Metcalfe J
Am J Vet Res. 1977 Dec;38(12):2089-90.
Pygmy goat blood was analyzed to determine hematologic base-line values. Male, female, and castrated male goats were used in this investigation. Influence of age on these variables was also studied. Most of the hematologic values of pygmy goats were similar to the reference values reported for several other ruminant species and for man. Values significantly different from reference values in man were as follows: Erythrocyte counts were slightly higher than for human beings. The relative lymphocyte count was comparable to that in infants, but significantly greater than values in adult human beings. Also, although not of statistical significance, hemoglobin levels in goats were slightly lower than in both infants and adult human beings, and the leukocyte count was just slightly higher than the usual values for infants and adult human beings. Thus, of 9 hematologic variables, only 1 was significantly different from those in man, and 2 were slightly different. The fact that pygmy goats have hematologic responses similar to those of man, and the similarity of hematologic values to reference values in man, further enhances the pygmy goat for use as an experimental animal.
对侏儒山羊的血液进行分析以确定血液学基线值。本研究使用了雄性、雌性和去势雄性山羊。还研究了年龄对这些变量的影响。侏儒山羊的大多数血液学值与报道的其他几种反刍动物和人类的参考值相似。与人类参考值有显著差异的值如下:红细胞计数略高于人类。相对淋巴细胞计数与婴儿相当,但显著高于成年人的值。此外,虽然没有统计学意义,但山羊的血红蛋白水平略低于婴儿和成年人,白细胞计数仅略高于婴儿和成年人的正常值。因此,在9项血液学变量中,只有1项与人类有显著差异,2项略有差异。侏儒山羊的血液学反应与人类相似,且血液学值与人类参考值相似,这一事实进一步提高了侏儒山羊作为实验动物的适用性。