塞浦路斯地中海贫血的预防。

Prevention of thalassaemia in Cyprus.

作者信息

Angastiniotis M A, Hadjiminas M G

出版信息

Lancet. 1981 Feb 14;1(8216):369-71. doi: 10.1016/s0140-6736(81)91682-2.

Abstract

A programme for the prevention of beta-homozygous thalassaemia has been operating in Cyprus from 1973. From 1976 there has been an increasing gap between the number of homozygotes born and the number expected, calculated as 1 in 135 of the total births. In 1978 23 homozygotes are known to have been born compared with 71 expected, and in 1979, 18 compared with 77 expected. All cases may not have yet to come to notice. the programme consists of public education, population screening, genetic counseling, and antenatal diagnosis.

摘要

自1973年以来，塞浦路斯一直在实施一项预防β型纯合子地中海贫血的计划。自1976年起，出生的纯合子数量与预期数量（按总出生数的1/135计算）之间的差距越来越大。1978年，已知有23名纯合子出生，而预期为71名；1979年，有18名出生，预期为77名。可能并非所有病例都已被发现。该计划包括公众教育、人群筛查、遗传咨询和产前诊断。