[Influence of S-methylmethionine on the metabolism of nucleic acids in Escherichia coli].
作者信息
Lebenka A Iu, Rachkus Iu A, Kanopkaite S I
出版信息
Vopr Med Khim. 1981 Mar-Apr;27(2):207-10.
PMID:6169200
Abstract
The influence of S-methylmethionine (SMM) on metabolism of nucleic acids in E. coli MRE-600 has been studied. The influence of SMM was compared with that of methionine. Addition of SMM to the medium at the concentration of 2.7 . 10(-5) M increased the incorporation of 5-methyl-3H-thymidine into DNA by about 20% and the incorporation of 2-14C-uridine into the total RNA of the cells by about 47%. The electrophoretic separation of RNA in polyacrylamide gels showed that SMM stimulated the incorporation of the label into 4 S, 5 S, 16 S and 23 S RNA with different intensity. The highest stimulation of the label incorporation has been observed in 16 S RNA.
摘要
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