粗糙脉孢菌中鸟氨酸氨甲酰基转移酶合成的跨途径调控
Cross-pathway control of ornithine carbamoyltransferase synthesis in Neurospora crassa.
作者信息
Kemp B F, Flint H J
出版信息
J Gen Microbiol. 1982 Jul;128(7):1503-7. doi: 10.1099/00221287-128-7-1503.
PMID:6214612
Abstract
The pattern of cross-pathway regulation of the arginine synthetic enzyme ornithine carbamoyltransferase was investigated in Neurospora crassa, using single and double mutant auxotrophic strains starved for their required amino acids. These experiments show that starvation for histidine, tryptophan, isoleucine, valine or arginine can result in derepression of ornithine carbamoyltransferase. Methionine starvation also gave slight derepression, but starvation for lysine or leucine gave little or no effect.
摘要
利用对所需氨基酸饥饿的单突变和双突变营养缺陷型菌株，研究了粗糙脉孢菌中精氨酸合成酶鸟氨酸氨甲酰转移酶的交叉途径调控模式。这些实验表明，组氨酸、色氨酸、异亮氨酸、缬氨酸或精氨酸饥饿可导致鸟氨酸氨甲酰转移酶的去阻遏。甲硫氨酸饥饿也会导致轻微的去阻遏，但赖氨酸或亮氨酸饥饿几乎没有影响或没有影响。
相似文献
1
Cross-pathway control of ornithine carbamoyltransferase synthesis in Neurospora crassa.
J Gen Microbiol. 1982 Jul;128(7):1503-7. doi: 10.1099/00221287-128-7-1503.
2
Depression of enzyme synthesis in response to arginine limitation in Neurospora crassa.
J Gen Microbiol. 1985 Nov;131(11):2891-900. doi: 10.1099/00221287-131-11-2891.
3
Cross-pathway regulation: tryptophan-mediated control of histidine and arginine biosynthetic enzymes in Neurospora crassa.
J Bacteriol. 1974 Sep;119(3):889-92. doi: 10.1128/jb.119.3.889-892.1974.
4
Cross-pathway regulation: histidine-mediated control of histidine, tryptophan, and arginine biosynthetic enzymes in Neurospora crassa.
J Bacteriol. 1974 Sep;119(3):893-98. doi: 10.1128/jb.119.3.893-898.1974.
5
General control of arginine biosynthetic enzymes in Neurospora crassa.
J Gen Microbiol. 1981 May;124(1):129-40. doi: 10.1099/00221287-124-1-129.
6
Effect of chloramphenicol and ethidium bromide on the level of ornithine carbamoyltransferase in Neurospora crassa.
J Bacteriol. 1986 May;166(2):679-82. doi: 10.1128/jb.166.2.679-682.1986.
7
Regulation of amino acid synthetic enzymes in Neurospora crassa in the presence of high concentrations of amino acids.
Mol Gen Genet. 1986 Jun;203(3):533-7. doi: 10.1007/BF00422082.
8
Control of the flux to arginine in Neurospora crassa: de-repression of the last three enzymes of the arginine pathway.
J Mol Biol. 1974 Aug 5;87(2):303-16. doi: 10.1016/0022-2836(74)90151-x.
9
cpc-2, a new locus involved in general control of amino acid synthetic enzymes in Neurospora crassa.
Curr Genet. 1990 Oct;18(3):211-5. doi: 10.1007/BF00318383.
10
Ornithine transcarbamylase from Neurospora crassa: purification and properties.
Arch Biochem Biophys. 1985 May 15;239(1):172-83. doi: 10.1016/0003-9861(85)90824-0.
引用本文的文献
1
Mechanisms of gene regulation in the general control of amino acid biosynthesis in Saccharomyces cerevisiae.
Microbiol Rev. 1988 Jun;52(2):248-73. doi: 10.1128/mr.52.2.248-273.1988.
Zotero 插件