表达一种AKR鼠白血病病毒gp71样抗原的骨髓细胞群体的特征分析。
Characterization of the bone marrow cell population expressing an AKR murine leukaemia-virus gp71-like antigen.
作者信息
Rubio N
出版信息
Immunology. 1981 Oct;44(2):339-45.
The murine bone marrow population mainly responsible for the unique competing activity of this lymphoid organ in the competition radioimmunoassay (cRIA) for AKR murine leukaemia viruses gp71 has been partially purified and characterized. That population could be distinguished by the following properties: (i)gp71+ cells (cell population expressing the AKR MuLV gp71 antigen) are mainly medium density cells, according to their distribution in the layers of a discontinuous bovine serum albumin (BSA) gradient; (ii) The gp71 positive cells are not mature lymphocytes; (iii) This cell population is found both in the FcR+ and FcR- compartments and is not included in the complement (C') receptor-positive population; and finally, (iv) the gp71+ cells are phagocytic cells and an adherent cell population according to its capacity to adhere to plastic surfaces, nylon wool and Sephadex G-10.
在针对AKR鼠白血病病毒gp71的竞争放射免疫分析（cRIA）中，对负责该淋巴器官独特竞争活性的小鼠骨髓群体进行了部分纯化和特性鉴定。该群体可通过以下特性加以区分：（i）根据gp71 +细胞（表达AKR MuLV gp71抗原的细胞群体）在不连续牛血清白蛋白（BSA）梯度各层中的分布情况，它们主要是中等密度细胞；（ii）gp71阳性细胞不是成熟淋巴细胞；（iii）该细胞群体在FcR +和FcR-区室中均有发现，且不包含在补体（C'）受体阳性群体中；最后，（iv）根据gp71 +细胞粘附于塑料表面、尼龙毛和葡聚糖凝胶G-10的能力，它们是吞噬细胞和贴壁细胞群体。
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