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[螺旋霉素;对人类的治疗价值。(作者译)]

[Spiramycin ; therapeutic value in humans. (author's transl)].

作者信息

Kernbaum S

出版信息

Sem Hop. 1982 Feb 4;58(5):289-97.

PMID:6277009
Abstract

Spiramycin gives high tissue levels and has very-few side-effects. It is one of the best antibiotics in infections of the upper and lower respiratory tract and of the oral cavity. It is probably one of the most effective antibiotics against chlamydia. Spiramycin is useful when toxoplasmosis occurs during pregnancy or results in severe diseases in non-immunodepressed patients. For the reasons listed above, we believe that spiramycin has been underestimated. This is the result of assessing its value according to its rather high MIC rather than to it's effectiveness against infection in animals and humans.

摘要

螺旋霉素在组织中浓度较高,且副作用极少。它是治疗上、下呼吸道及口腔感染的最佳抗生素之一。它可能是对抗衣原体最有效的抗生素之一。当妊娠期发生弓形虫病或在非免疫抑制患者中导致严重疾病时,螺旋霉素很有用。基于上述原因,我们认为螺旋霉素一直被低估了。这是根据其相对较高的最低抑菌浓度而非其对动物和人类感染的有效性来评估其价值的结果。

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