黑腹果蝇中的遗传不稳定性：插入序列诱导的缺失
Genetic instability in Drosophila melanogaster: deletion induction by insertion sequences.
作者信息
Green M M
出版信息
Proc Natl Acad Sci U S A. 1982 Sep;79(17):5367-9. doi: 10.1073/pnas.79.17.5367.
Abstract
Females of Drosophila melanogaster heteroallelic or homoallelic for X chromosome giant (gt) mutants generate deletions involving the wild-type alleles at two X chromosome gene loci: yellow body color (y) and white eye color (w). The deletions, bidirectional in the case of y and with fixed endpoint in the case of w, are associated with particular X chromosomes. Distinctive insertion sequences, located proximal to the target loci, are presumed to generate the deletions.
摘要
黑腹果蝇X染色体巨型（gt）突变体的杂合等位基因或纯合等位基因雌性会产生涉及两个X染色体基因位点野生型等位基因的缺失：黄体色（y）和白眼色（w）。这些缺失在y的情况下是双向的，在w的情况下具有固定的端点，与特定的X染色体相关。位于靶位点近端的独特插入序列被认为会产生这些缺失。
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