Rao P N, Prendiville V, Buxton A, Moss D G, Blacklock N J
Br J Urol. 1982 Dec;54(6):578-83. doi: 10.1111/j.1464-410x.1982.tb13600.x.
Three hundred and ninety-two stone formers were investigated to exclude systemic disorders and to define the presence of haematological and urinary abnormality commonly associated with stone disease. Increased urinary excretion of calcium, oxalate or uric acid was found in 40% and there was more than one abnormality in 16% of the patients. The dietary habit of stone formers did not differ significantly from that of control subjects. Dietary advice to increase the consumption of fibre and reduce the consumption of sugar, refined carbohydrates and animal protein produced a significant reduction in the urinary excretion of calcium, oxalate and uric acid. We consider that reduction of the nutrient density of the diet by this means is the first line of management of idiopathic stone formers.
对392名结石患者进行了调查,以排除全身性疾病,并确定与结石病常见相关的血液学和尿液异常情况。40%的患者发现尿钙、草酸或尿酸排泄增加,16%的患者存在不止一种异常情况。结石患者的饮食习惯与对照组无显著差异。增加纤维摄入、减少糖、精制碳水化合物和动物蛋白摄入的饮食建议使尿钙、草酸和尿酸排泄显著减少。我们认为,通过这种方式降低饮食的营养密度是特发性结石患者的一线治疗方法。