使用犬类连续细胞系（A-72）对猫冠状病毒中和活性进行微量滴定测定。
Macrotiter assay for coronavirus-neutralizing activity in cats using a canine continuous cell line (A-72).
作者信息
Barlough J E, Jacobson R H, Scott F W
出版信息
Lab Anim Sci. 1983 Dec;33(6):567-70.
PMID:6319813
Abstract
A heterologous neutralization assay for feline infectious peritonitis virus serology was developed using a single continuous cell line of canine origin, A-72, which is susceptible to cytopathic infection with both transmissible gastroenteritis virus of pigs and canine coronavirus. Of several coronavirus isolates tested, the 1-71 isolate of canine coronavirus demonstrated the most effective neutralization by serum and body fluids of cats with histopathologically confirmed feline infectious peritonitis.
摘要
利用源自犬的单一连续细胞系A-72开发了一种用于猫传染性腹膜炎病毒血清学的异源中和试验，该细胞系对猪传染性胃肠炎病毒和犬冠状病毒的细胞病变感染均敏感。在测试的几种冠状病毒分离株中，犬冠状病毒的1-71分离株在组织病理学确诊为猫传染性腹膜炎的猫的血清和体液中表现出最有效的中和作用。
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