酵母中肽转运的光亲和抑制作用
Photoaffinity inhibition of peptide transport in yeast.
作者信息
Sarthou P, Gonneau M, Le Goffic F
出版信息
Biochem Biophys Res Commun. 1983 Feb 10;110(3):884-9. doi: 10.1016/0006-291x(83)91044-6.
PMID:6340670
Abstract
A photoaffinity label, 4-azidobenzoyltrimethionine has been synthesized. It competitively inhibits trimethionine uptake in the yeast C. albicans. Upon UV irradiation it irreversibly and specifically blocks oligopeptide uptake. These results give the first example of photoinhibition of peptide uptake in yeast.
摘要
一种光亲和标记物4-叠氮苯甲酰基三甲硫氨酸已被合成。它能竞争性抑制白色念珠菌酵母中三甲硫氨酸的摄取。经紫外线照射后，它会不可逆地、特异性地阻断寡肽摄取。这些结果给出了酵母中肽摄取光抑制的首个实例。
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