Van Lysel M S, Dobbins J T, Peppler W W, Hasegawa B H, Lee C S, Mistretta C A, Zarnstorff W C, Crummy A B, Kubal W, Bergsjordet B, Strother C M, Sackett J F
Radiology. 1983 Jun;147(3):869-74. doi: 10.1148/radiology.147.3.6342038.
Initial clinical results using a digital fluoroscopic implementation of the combined time-energy ("hybrid") subtraction technique are described, with emphasis on carotid and renal imaging. Where patient motion artifacts are due to soft-tissue motion alone, hybrid subtraction can remove them. Due to the need for a finite separation time between high- and low-energy pairs, however, the present implementation of the hybrid technique is not completely immune to soft-tissue motion. The intrinsic signal-to-noise ratio of hybrid imaging is less than that of conventional temporal subtraction. However, since the low-energy temporal subtraction images are included in the hybrid data set, the diagnostic quality of the examination is not compromised.